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Merck

MAB5408

Anti-Histamine Antibody, pain

Chemicon®, from mouse

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About This Item

eCl@ss:
32160702
UNSPSC Code:
12352203

Product Name

Anti-Histamine Antibody, pain, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

monoclonal

species reactivity (predicted by homology)

all

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

isotype

IgA

shipped in

dry ice

target post-translational modification

unmodified

Application

ELISA: 1:500-1:2,500

Immunohistochemistry: 1:1,000-1:2,500

Optimal working dilutions must be determined by end user.
Research Category
Inflammation & Immunology
Research Sub Category
Inflammation & Autoimmune Mechanisms
This Anti-Histamine Antibody, pain is validated for use in IC, IH for the detection of Histamine.

Biochem/physiol Actions

Histamine

The cross-reactivities were determined using an ELISA test by competition experiments with the following compounds:

Compound Cross-reactivity

Histamine-HD-BSA 1

1-Methyl-Histamine-HD-BSA 1

Histamine-G-BSA 1/>50,000

Histamine-GA-BSA 1/>50,000

Abbreviations:

(HD) Hexamethylene diisocyanate

(G) Glutaraldehyde

(GA) Glutaric anhydride

(BSA) Bovine Serum Albumin

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Histamine-Hexamethylene diisocyanate-BSA.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.05% sodium azide.

Preparation Note

Maintain at -20°C in undiluted aliquots for 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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COVID-19-associated chilblain pruritus is non-histaminergic mediated and correlated to epidermal interleukin 31.
Angelina Labib et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 37(7), e818-e820 (2023-02-15)
Neuroimmune Mediators of Pruritus in Hispanic Scalp Psoriatic Itch.
Nattkemper, et al.
Acta Dermato-Venereologica, 103, adv4463-adv4463 (2023)
Lars Freudenmacher et al.
The Journal of comparative neurology, 528(6), 972-988 (2019-10-17)
Whereas our understanding of the dopaminergic system in mammals allows for a distinction between ventral tegmental area (VTA) and substantia nigra pars compacta (SNc), no clear evidence for separate structures in anamniotes has been presented to date. To broaden the

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