MAB5540
Anti-Olig1 Antibody
ascites fluid, Chemicon®
Synonym(s):
Oligo1, Oligodendrocyte transcription factor 1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Product Name
Anti-Olig1 Antibody, ascites fluid, Chemicon®
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
monoclonal
species reactivity
human, mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... OLIG1(116448)
rat ... Olig1(60394)
Analysis Note
Control
Positive control: Corpus callosium Negative control: skin or non-neural organs
Positive control: Corpus callosium Negative control: skin or non-neural organs
Application
Anti-Olig1 Antibody is an antibody against Olig1 for use in WB, IC, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neuronal & Glial Markers
Neuronal & Glial Markers
Biochem/physiol Actions
Oligodendrocyte marker Olig1. The antibody typically stains cell in either the cytoplasm or nucleus depending on cell type. Staining will be present in the nucleus of remyelinating oligodendrocytes.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
Olig-1 is a bHLH transcription factor that is expressed by oligodendrocytes in the brain where it promotes oligodendrocyte formation and maturation. Olig1 cooperates with Olig2 to establish the pMN domain of the embryonic neural tube.
Immunogen
Fusion protein from mouse Olig1.
Physical form
Liquid ascites fluid.
Preparation Note
Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Mario Marotta et al.
Stem cell research, 22, 33-42 (2017-06-05)
Despite benefits of prenatal in utero repair of myelomeningocele, a severe type of spina bifida aperta, many of these patients will still suffer mild to severe impairment. One potential source of stem cells for new regenerative medicine-based therapeutic approaches for
Hong Zhao et al.
Molecular medicine reports, 20(5), 4603-4611 (2019-11-09)
The differentiation and maturation of oligodendrocyte precursor cells (OPCs) is important for remyelination in the central nervous system. Nevertheless, this process is often limited and incomplete in ischemic injury. Oligodendrocyte transcription factor 1 (Olig1) is important for the maturation of OPCs and
Disruption of glial cell development by Zika virus contributes to severe microcephalic newborn mice.
Cui Li et al.
Cell discovery, 4, 43-43 (2018-08-08)
The causal link between Zika virus (ZIKV) infection and microcephaly has raised alarm worldwide. Microglial hyperplasia, reactive gliosis, and myelination delay have been reported in ZIKV-infected microcephalic fetuses. However, whether and how ZIKV infection affects glial cell development remain unclear.
Elena K Fetisova et al.
Oxidative medicine and cellular longevity, 2019, 2082561-2082561 (2019-07-30)
Multiple sclerosis (MS) is a heterogeneous autoimmune disease of unknown etiology characterized by inflammation, demyelination, and axonal degeneration that affects both the white and gray matter of CNS. Recent large-scale epidemiological and genomic studies identified several genetic and environmental risk
Jenna J Boulanger et al.
Frontiers in neuroscience, 11, 143-143 (2017-04-13)
Key Points Oligodendrocyte precursor cells express doublecortin, a microtubule-associated protein.Oligodendrocyte precursor cells express doublecortin, but at a lower level of expression than in neuronal precursor.Doublecortin is not associated with a potential immature neuronal phenotype in Oligodendrocyte precursor cells. Oligodendrocyte precursor
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MAB5540 | 04053252666728 |
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