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Merck

MAB80138

Anti-Human Metapneumovirus Antibody, clone 507

clone 507, Chemicon®, from mouse

Synonym(s):

hMPV

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Human Metapneumovirus Antibody, clone 507, clone 507, Chemicon®, from mouse

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

507, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
western blot: suitable

isotype

IgG2a

shipped in

wet ice

Quality Level

300

Related Categories

Application

Detect Human Metapneumovirus using this Anti-Human Metapneumovirus Antibody, clone 507 validated for use in ELISA, FC, IF & WB.

Biochem/physiol Actions

Recognizes the nuclear protein. Reactive with all hMPV sub-types; A1, A2, B1, B2.

General description

Human metapneumovirus (hMPV) is a member of the pneumovirinae subfamily of paramyxoviruses, first described in 2001 from pediatric respiratory specimens in the Netherlands. It is an enveloped pleomorphic virus with a single negative-strand RNA genome. Two major serotypes, A and B, have been described. Several studies identified hMPV in specimens worldwide, and estimated that by age 5 years 70% of children have developed antibodies to hMPV.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Estimates of individuals exposed to human metapneumovirus in a community-based Taiwanese population in 1999.
Chung-Guei Huang,Kuo-Chien Tsao,Tzou-Yien Lin,Yhu-Chering Huang,Li-Ang Lee,Tzu-Hou Chen et al.
Archives of Virology null
Simon Loevenich et al.
Mediators of inflammation, 2019, 4964239-4964239 (2019-11-07)
Human metapneumovirus (HMPV) may cause severe respiratory disease. The early innate immune response to viruses like HMPV is characterized by induction of antiviral interferons (IFNs) and proinflammatory immune mediators that are essential in shaping adaptive immune responses. Although innate immune
Xiaoyan Li et al.
Intervirology, 58(6), 403-412 (2016-04-21)
No licensed vaccines or therapeutic agents for human metapneumovirus (hMPV) infection exist to date. We aimed to construct a multi-epitope peptide (MEP) of hMPV to show promising results for epitope-based vaccine development. Six independent algorithms were screened to predict B-cell
C Garrett Rappazzo et al.
Immunity, 55(9), 1710-1724 (2022-08-10)
Human metapneumovirus (hMPV) is a leading cause of acute lower respiratory tract infections in high-risk populations, yet there are no vaccines or anti-viral therapies approved for the prevention or treatment of hMPV-associated disease. Here, we used a high-throughput single-cell technology
B G van den Hoogen et al.
Nature medicine, 7(6), 719-724 (2001-06-01)
From 28 young children in the Netherlands, we isolated a paramyxovirus that was identified as a tentative new member of the Metapneumovirus genus based on virological data, sequence homology and gene constellation. Previously, avian pneumovirus was the sole member of
View All Related Papers

Global Trade Item Number

SKUGTIN
MAB8013804053252725272

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