MABC121
Anti-ALDH3A1, clone 10C7.1 Antibody
clone 10C7.1, from mouse
Synonym(s):
Aldehyde dehydrogenase, dimeric NADP-preferring, ALDHIII, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
10C7.1, monoclonal
Species reactivity:
human
Application:
IHC, WB
Citations:
1
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
10C7.1, monoclonal
species reactivity
human
technique(s)
immunohistochemistry: suitable, western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ALDH3A1(218)
General description
Aldehyde dehydrogenase family 3 member A1 (ALDH3A1 or Aldh3A1) is a member of the aldehyde dehydrogenase (ALDH) superfamily. The ALDH family is a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. ALDHs are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. They are suggested to play a major role in the detoxification of alcohol-derived acetaldehyde. ALDH3A1 is shown to oxidize preferentially aromatic aldehyde substrates, and it may play a role in the oxidation of toxic aldehydes. ALDH3A1 is highly expressed in stomach, esophagus, lung, and cornea. It represents between 5 to 50% of the water soluble protein fraction in mammalian corneas and it is implied to protect the cornea from UV-induced oxidative stress.
~50 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
Immunogen
GST-tagged recombinant protein corresponding to the N-terminus of human ALDH3A1.
Application
Detect Aldehyde Dehydrogenase using this mouse monoclonal antibody, Anti-ALDH3A1, clone 10C7.1 Antibody validated for use in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ALDH3A1 in human stomach and lung tissues.
Physical form
Format: Purified
Analysis Note
Evaluated by Western Blotting in A549 cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected ALDH3A1 in 10 µg of A549 cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected ALDH3A1 in 10 µg of A549 cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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