Skip to Content
Merck

MABE933

Anti-Tudor-SN Antibody, clone 13.14.1

clone 13.14.1, 1 mg/mL, from mouse

Synonym(s):

Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator, EBNA2 coactivator p100, Tudor domain-containing protein 11, p100 co-activator, Tudor-SN

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Anti-Tudor-SN Antibody, clone 13.14.1, clone 13.14.1, 1 mg/mL, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

13.14.1, monoclonal

species reactivity

human

concentration

1 mg/mL

technique(s)

western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_055205

UniProt accession no.

Q7KZF4

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... SND1(27044)

Analysis Note

Evaluated by Western Blotting in HEK-293 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Tudor-SN in 10 µg of HEK-293 cell lysate.

Application

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Nuclear Receptors
This Anti-Tudor-SN Antibody, clone 13.14.1 is validated for use in Western Blotting for the detection of Tudor-SN.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Tudor-SN in 10 µg of HeLa cell lysate.
Western Blotting Analysis: A representative lot detected Tudor-SN in HeLa and Hek 293 cell lysate (Ota, H., et al. (2013). Cell. 153:575-589).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Tudor-SN, also known as Staphylococcal nuclease domain-containing protein 1, 100 kDa coactivator or EBNA2 coactivator p100 or Tudor domain-containing protein 11 or p100 co-activator, and encoded by the gene name SND1 or TDRD11, plays an important role in PIM1 regulation of MYB acitivity and acts as a transcriptional activatior of EBNA-2. SND1 also interacts with EAV, NSP1,GTF2E1 and GTF2E2, and forms a ternary complex with STAT6 and POLR2A. SND1 ic localized to the cytoplasm and in IL-4 stimulated cells SND1 co-localizes with STAT6 in the nucleus. SND1 plays an important role in the assembly of STAT6 transcriptome and stimulates IL-4-dependent transcription by mediating interaction between STAT6 and CBP.
~110 kDa observed. The calculated molecular weight of this protein is 101 kDa, but can be observed at ~110 kDa due to post transitional modifications.

Immunogen

Epitope: C-terminus
Recombinant protein corresponding to the C-terminus of human Tudor-SN.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Not finding the right product?  

Try our Product Selector Tool.

Storage Class

10 - Combustible liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service