Skip to Content
Merck

PF126

Bcl-2, C-Terminal Truncated, His•Tag®, Human, Recombinant, E. coli

Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His•Tag sequence, and expressed in E. coli.

Sign In to View Organizational & Contract Pricing.

Select a Size

All Photos(1)

About This Item

NACRES:
NA.77
UNSPSC Code:
12352202

Product Name

Bcl-2, C-Terminal Truncated, His•Tag®, Human, Recombinant, E. coli, Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His•Tag sequence, and expressed in E. coli.

form

liquid

biological source

human

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

species reactivity

human

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
avoid repeated freeze/thaw cycles

dilution

(Neutralization (see biological activity))

shipped in

wet ice

storage temp.

−20°C

Quality Level

100

Application

Neutralization (see biological activity)

Biochem/physiol Actions

EC₅₀ = 100-300 nM based on its ability to inhibit 54 nM caspase-8-cleaved human Bid-mediated release of cytochrome c from isolated mouse liver mitochondria

Disclaimer

Toxicity: Standard Handling (A)

General description

Recombinant, human Bcl-2 without the 17 amino acid mitochondrial targeting sequence at the C-terminus, fused to a His•Tag sequence, and expressed in E. coli. The truncated protein retains the ability to neutralize pro-apoptotic Bcl-2 family members.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In 100 mM KCl, 10 mM HEPES, 20% glycerol, pH 8.0.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service