ED2SS

Ethylenediaminetetraacetic acid disodium salt dihydrate

Name: Ethylenediaminetetraacetic acid disodium salt dihydrate
Brand: SIAL

reagent grade, 98.5-101.5% (titration)

Synonym(s):

Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na₂, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na₂

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₄N₂Na₂O₈ · 2H₂O

CAS Number:

6381-92-6

Molecular Weight:

372.24

NACRES:

NA.77

PubChem Substance ID:

24894708

UNSPSC Code:

12352107

EC Number:

205-358-3

Beilstein/REAXYS Number:

3900609

Product Name

Ethylenediaminetetraacetic acid disodium salt dihydrate, reagent grade, 98.5-101.5% (titration)

InChI key

OVBJJZOQPCKUOR-UHFFFAOYSA-L

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

SMILES string

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

biological source

synthetic (organic)

grade

reagent grade

agency

suitable for SM 4500 - NH3

assay

98.5-101.5% (titration)

form

powder

reaction suitability

reagent type: chelator

mp

248 °C (dec.) (lit.)

solubility

H₂O: soluble, clear, colorless

application(s)

agriculture
clinical research

storage temp.

room temp

Quality Level

200

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Related Categories

Biochemicals

Chelating & Reducing Agents for Research

Application

Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.

Ethylenediaminetetraacetic acid disodium salt dihydrate has been used as a component of the plasma membrane resuspension buffer, inhibitor′s preservative solution (IS) and luciferase activity assay mix.

Features and Benefits

Reagent grade for general lab use

General description

Ethylenediaminetetraacetic acid (EDTA) disodium salt is an aminopolycarboxylic acid and a hexadentate ligand. It chelates metal cations to form a stable octahedral complex. It is commonly added to buffers, solutions, and even soil samples to control the concentrations of metal ions or to remove metal contaminants. Metal chelators play a crucial role in various research applications, such as biochemistry, molecular biology, and analytical chemistry. For example, EDTA is a blood anticoagulant that chelates calcium ions in the blood, this inhibits clots and is routinely used in hematological assays.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H332,H373

pcodes

P260 - P271 - P304 + P340 + P312 - P314 - P501

Hazard Classifications

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

target_organs

Respiratory Tract

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Isolation of plasma membrane-associated membranes from rat liver

Suski JM, et al.

Nature Protocols, 9(2), 312-312 (2014)

Measurement of free IGF-I saliva levels: perspectives in the detection of GH/IGF axis in athletes

Antonelli G, et al.

Clinical Biochemistry, 40(8), 545-550 (2007)

Conazole fungicides inhibit Leydig cell testosterone secretion and androgen receptor activation in vitro.

Roelofs MJE, et al.

Toxicology Reports, 1, 271-283 (2014)

EDTA chelation therapy for cardiovascular disease: a systematic review

Seely DMR, et al.

BMC Cardiovascular Disorders, 5(1), 32-32 (2005)

Ethylenediaminetetraacetic acid induces antioxidant and anti-inflammatory activities in experimental liver fibrosis

Gonzalez-Cuevas J, et al.

Redox Report, 16(2), 62-70 (2011)

View All Related Papers

Protocols

Enzymatic Assay & ATP Sensitivity Test of Luciferase

Measure luciferase activity using a luminometer assay detecting light emission, with applications in ATP detection and genetic function reporting.