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Merck

F9005

Flufenamic acid

analytical standard, for drug analysis

Synonym(s):

N-(3-[Trifluoromethyl]phenyl)anthranilic acid, N-(α,α,α-Trifluoro-m-tolyl)anthranilic acid

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About This Item

Linear Formula:
2-(CF3C6H4NH)C6H4CO2H
CAS Number:
530-78-9
Molecular Weight:
281.23
NACRES:
NA.24
PubChem Substance ID:
329799777
UNSPSC Code:
41116107
EC Number:
208-494-1
MDL number:
MFCD00002422

Product Name

Flufenamic acid, analytical standard, for drug analysis

InChI key

LPEPZBJOKDYZAD-UHFFFAOYSA-N

InChI

1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)

SMILES string

OC(=O)c1ccccc1Nc2cccc(c2)C(F)(F)F

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

132-135 °C (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

Quality Level

100

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Application

Flufenamic acid has been used as a standard in studying the two well defined, polymorphs of flufenamic acid like form I and form III, using solid-state density functional theory and terahertz spectroscopy.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Flufenamic acid, a non-steroidal anti-inflammatory drug, is an effective analgesic agent.

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN1442
BCCL7651
BCCK1277
BCCK8356
BCCJ5571

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Antonella Di Pizio et al.
Cellular and molecular life sciences : CMLS, 77(3), 531-542 (2019-06-27)
Human bitter taste receptors (TAS2Rs) are a subfamily of 25 G protein-coupled receptors that mediate bitter taste perception. TAS2R14 is the most broadly tuned bitter taste receptor, recognizing a range of chemically diverse agonists with micromolar-range potency. The receptor is
Julia C Schwarz et al.
International journal of pharmaceutics, 437(1-2), 83-88 (2012-08-21)
Nanocarriers are highly interesting delivery systems for the dermal application of drugs. Based on a eudermic alkylpolyglycosid nanoemulsions, solid lipid nanoparticles (SLN) and nano-structured lipid carriers (NLC) were prepared by ultrasonic dispersion. The ultrasound preparation technique turned out to be
Conformational origins of polymorphism in two forms of flufenamic acid
Delaney P S, et al.
Journal of Molecular Structure, 1078, 83-89 (2014)
Minsoo Kim et al.
Pharmaceutics, 11(3) (2019-03-22)
Concomitant use of rivaroxaban with non-dihydropyridine calcium channel blockers (non-DHPs) might lead to an increase of systemic rivaroxaban exposure and anticoagulant effects in relation to the inhibition of metabolic enzymes and/or transporters by non-DHPs. This study was designed to evaluate
Jon Andoni Sánchez et al.
Immunobiology, 222(2), 241-250 (2016-10-11)
Previous works with autumnalamide reported that Store Operated Calcium (SOC) channels were blocked through mitochondrial modulation. In the present paper we studied the effect of autumnalamide on ionomycin Ca2+ fluxes. Thus, autumnalamide did not modify ionomycin-sensitive intracellular pools while the
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