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Merck

PVP40

Polyvinylpyrrolidone

average mol wt 40,000

Synonym(s):

PVP, Polyvidone, Povidone

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About This Item

Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
NACRES:
NA.25
PubChem Substance ID:
24899319
UNSPSC Code:
12161700
MDL number:
MFCD00149016

Product Name

Polyvinylpyrrolidone, average mol wt 40,000

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

SMILES string

C=CN1CCCC1=O

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

biological source

synthetic (oragnic)

form

powder

mol wt

average mol wt 40,000

impurities

<5.0% water (Karl Fischer)

viscosity number

29-32(lit.)

solubility

water: 100 mg/mL, clear, colorless to light yellow

application(s)

agriculture

Quality Level

200

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Other Notes

For additional information on our range of Biochemicals, please complete this form.
Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Application

Polyvinylpyrrolidone has been used in the purification of glutamine synthetases from plant samples. It has been used to block the PVDF (polyvinylidene difluoride) membrane and to avoid nonspecific binding.

Features and Benefits

  • Highly versatile surfactant for your life science and biochemical research
  • Excellent Solubilizing agent and Complexing agent

General description

Polyvinylpyrrolidone (PVP) can form complexes with phenolics and alkaloids. The complex formation allows removal of phenolics and alkaloids from plant samples, thereby inhibiting any modification of proteins by them and any hindrance they may cause in spectrophotometric determinations of protein content. PVP might also enhances the stability of enzymes.
Polyvinylpyrrolidone (PVP), a multifunctional synthetic polymer, finds utility in life science and biochemical research. This water-soluble polymer is versatile, serving as a stabilizing agent, emulsifier, suspending agent, solubilizing agent, protective colloid, and complexing agent. Its protective colloid properties are particularly valuable in stabilizing proteins, enzymes, and other biological substances.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
WXBF7721V
WXBF7431V
WXBF7100V
0000482337
0000478919

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Structural analysis of N- and O-glycans released from glycoproteins.
Jensen PH et al.
Nature Protocols, 7, 1299-1299 (2012)
Manna Crespan et al.
Scientific reports, 10(1), 7206-7206 (2020-05-01)
'Glera' and 'Ribolla Gialla' are the most economically relevant local grapevine cultivars of Friuli Venezia Giulia region (north-eastern Italy). 'Glera' is used to produce the world-renowned Prosecco wine. 'Ribolla Gialla' cultivation is constantly increasing due to the strong demand for
Glutamine Synthetases of Higher Plants : Evidence for a Specific Isoform Content Related to Their Possible Physiological Role and Their Compartmentation within the Leaf.
McNally SF et al.
Plant Physiology, 72, 22-22 (1983)
Quantification of the Antioxidant Activity in Salt-Stressed Tissues.
Maksimovic JJD and Zivanovic BD
Plant Salt Tolerance: Methods and Protocols, 237-237 (2012)
Angiotensin II inhibits insulin signaling in aortic smooth muscle cells at multiple levels. A potential role for serine phosphorylation in insulin/angiotensin II crosstalk.
Folli F et al.
The Journal of Clinical Investigation, 100, 2158-2158 (1997)
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