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Merck

T7875

Thiourea

≥99.0%, ReagentPlus®

Synonym(s):

Sulfourea, Thiocarbamide

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About This Item

Linear Formula:
NH2CSNH2
CAS Number:
Molecular Weight:
76.12
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
200-543-5
MDL number:
Beilstein/REAXYS Number:
605327

Product Name

Thiourea, ReagentPlus®, ≥99.0%

InChI key

UMGDCJDMYOKAJW-UHFFFAOYSA-N

InChI

1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)

SMILES string

NC(N)=S

product line

ReagentPlus®

assay

≥99.0%

mp

170-176 °C (lit.)

functional group

amine
thiourea

Quality Level

Gene Information

mouse ... Ephx2(13850)

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Application

Chaotropic agent; strong denaturant. Increases solubility and recovery of proteins
Thiourea has been used:
  • as a component in ice cold sample buffer for protein analysis
  • in intracellular extraction buffer for the extraction of soluble intracellular proteins
  • as a component of electrophoresis buffer

Biochem/physiol Actions

Thiourea is a free radical scavenger of the peroxide radical. It was shown to inhibit lipid peroxidation and ultraviolet (UV)-induced crosslinking of collagen. Bud dormancy in plants can be inhibited by thiourea, which is used as a growth stimulator. It is also known to be used in the treatment of hyperthyroidism.

General description

Thiourea is an analogue of urea, containing sulphur.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Extraction of Intracellular and Cell Wall Proteins from Leaves and Roots of Harsh Hakea
Shane MW and Plaxton WC
Journal of Experimental Botany (2014)
Synergistic effects of glucose and ultraviolet irradiation on the physical properties of collagen
Ohan MP, et al.
Journal of Biomedical Materials Research, 60(3), 384-391 (2002)
Feline hypertrophic cardiomyopathy associated with the p. A31P Mutation in cMyBP-C is caused by production of mutated cMyBP-C with reduced binding to actin
Godiksen MTN, et al.
Open Journal of Veterinary Medicine, 3(02), 95-95 (2013)
Protocol: Optimised methodology for isolation of nuclei from leaves of species in the Solanaceae and Rosaceae families
Sikorskaite S, et al.
Plant methods, 9(1), 31-31 (2013)
Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium
Osunlaja AA
International Journal of ChemTech Research, 4(2), 609-617 (2012)

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