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Merck

S8875

Sodium bicarbonate

ReagentPlus®, ≥99.5%, powder

Synonym(s):

Sodium hydrogen carbonate

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About This Item

Linear Formula:
NaHCO3
CAS Number:
144-55-8
Molecular Weight:
84.01
UNSPSC Code:
12352302
NACRES:
NA.21
PubChem Substance ID:
329824613
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
MFCD00003528
assay:
≥99.5%
form:
powder

Product Name

Sodium bicarbonate, ReagentPlus®, ≥99.5%, powder

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

SMILES string

[Na+].OC([O-])=O

agency

suitable for EPA 300

product line

ReagentPlus®

assay

≥99.5%

form

powder

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

density

2.16 g/mL at 25 °C (lit.)

Quality Level

200

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Application

Sodium bicarbonate can be used as a catalyst:     
  • To synthesize nitriles from the corresponding aldehydes and hydroxylamine hydrochloride in the presence of sodium sulfate as a co-catalyst.      
  • To prepare coumarin derivatives via intramolecular Wittig reaction of substituted 2-formylphenyl 2-bromoacetates.      
  • In the acetylation of primary alcohols and phenols by reacting with acetic anhydride.

General description

Sodium bicarbonate is commonly known as baking soda. It serves as a source of carbon dioxide and is used to prepare a variety of sodium salts. It is also an important pH-regulating agent.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT4101
SHBT1809
SHBT1810
0000500140
0000500148

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Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
Somjot S Brar et al.
Clinical journal of the American Society of Nephrology : CJASN, 4(10), 1584-1592 (2009-08-29)
Infusion of sodium bicarbonate has been suggested as a preventative strategy but reports are conflicting on its efficacy. The aim of this study was to assess the effectiveness of hydration with sodium bicarbonate for the prevention of contrast-induced acute kidney
Joshua C Tremblay et al.
The Journal of physiology, 593(3), 723-737 (2014-11-25)
Blood flow through intrapulmonary arteriovenous anastomoses (IPAVA) is increased by acute hypoxia during rest by unknown mechanisms. Oral administration of acetazolamide blunts the pulmonary vascular pressure response to acute hypoxia, thus permitting the observation of IPAVA blood flow with minimal
Sophia Zoungas et al.
Annals of internal medicine, 151(9), 631-638 (2009-11-04)
Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). To determine the effect of sodium bicarbonate on the risk for CIN. MEDLINE, PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials from 1950 to
Eric A J Hoste et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 25(3), 747-758 (2009-08-26)
There have been conflicting reports on the use of intravenous administration of sodium bicarbonate for prevention of contrast-induced acute kidney injury (CI-AKI). The aim of this study was to evaluate the use of sodium bicarbonate for prevention of CI-AKI. This
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