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Merck

P8563

Polyuridylic acid–Agarose

lyophilized powder, matrix polyacrylhydrazido-agarose

Synonym(s):

Poly(U)–Agarose potassium salt

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About This Item

UNSPSC Code:
41106500
NACRES:
NA.56
MDL number:
Technical Service
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form

lyophilized powder

Quality Level

extent of labeling

0.1-1.0 mg per mL

matrix

polyacrylhydrazido-agarose

matrix attachment

ribose moiety after periodate oxidation

swelling

1 g swells to ~4 mL

capacity

≥0.2 mg/mL binding capacity (poly(A) (P 9403))

storage temp.

−20°C

Application

Polyuridylic acid-agarose is used in protein chromatography, affinity chromatography and specialty resins. Polyuridylic acid has been used to study insulin receptors and to develop polyclonal antibodies against RNase L.

Physical form

Lyophilized powder stabilized with lactose


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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S H Kim et al.
The EMBO journal, 11(6), 2319-2326 (1992-06-01)
Unlike autocatalyzed self-splicing reactions, nuclear pre-mRNA splicing requires transacting macromolecules and ATP. A protein encoded by the PRP2 gene of Saccharomyces cerevisiae is required, in conjunction with ATP, for the first cleavage-ligation reaction of pre-mRNA splicing. In this study, we
E A Zemskov et al.
Journal of virology, 74(15), 6784-6789 (2000-07-11)
The Bombyx mori nucleopolyhedrovirus (BmNPV) genome contains five related members of the bro gene family, all of which are actively expressed in infected BmN cells. Although their functions are unknown, their amino acid sequences contain a motif found in all
Shijun Cheng et al.
The Journal of biological chemistry, 282(35), 25247-25258 (2007-07-04)
The poly(A)-binding protein (PABP), a protein that contains four conserved RNA recognition motifs (RRM1-4) and a C-terminal domain, is expressed throughout the eukaryotic kingdom and promotes translation through physical and functional interactions with eukaryotic initiation factor (eIF) 4G and eIF4B.