1.37000
Acetic acid
100%, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP
Synonym(s):
Glacial acetic acid
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About This Item
Quality Level
agency
BP, ChP, JP, Ph. Eur., USP
vapor density
2.07 (vs air)
product line
EMPROVE® EXPERT
assay
100%
form
liquid
autoignition temp.
800 °F
expl. lim.
16 %, 92 °F, 4 %, 59 °F
technique(s)
API processing | salt formation: suitable
impurities
endotoxins, low
refractive index
n20/D 1.371 (lit.)
pH
2.5 (20 °C, 50 g/L in H2O)
bp
117-118 °C (lit.)
mp
16.2 °C (lit.)
solubility
602.9 g/L at 25 °C (at 1.013 hPa - completely soluble in water)
density
1.04 g/mL at 25 °C (lit.)
application(s)
liquid formulation
parenterals
pharma/biopharma processes
pharmaceutical
storage temp.
15-25°C
SMILES string
[F2C(F2C)13F3C]C(O)=O
InChI
1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)
InChI key
QTBSBXVTEAMEQO-UHFFFAOYSA-N
General description
As a result, you can integrate our solutions directly into your biopharmaceutical production process. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs.
Application
- As a buffering agent for the chromatography and purification processes of proteins and other biological products.
- As a counter ion, enhancing the solubility and other physicochemical properties of active pharmaceutical ingredients (APIs).
- To reduce the pH during virus inactivation process.
- As a stabilizer during the final formulation of APIs.
- In cleaning in place (CIP) applications as well as for pH adjustment.
Features and Benefits
- Comprehensive, up-to-date documentation you need to navigate regulatory challenges, manage risks, and improve processes.
- Suitable for higher-risk applications where the lowest microbiological and endotoxin levels are of utmost importance.
- Emprove® products are designed to facilitate compliance with global regulations (e.g., ICH Q7, EU GMP, USP, EP).
- Detailed supply chain and manufacturing information helps ensure traceability and continuity, which is critical for GMP manufacturing.
Legal Information
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signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1A
Storage Class
3 - Flammable liquids
flash_point_f
102.2 °F - closed cup
flash_point_c
39 °C - closed cup
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Articles
Instead of addressing API solubility during formulation, tackle it early during development. Read about the various methods for API processing.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 1.37000.9010 | 04027269240141 |
| 1.37000.2500 | 04027269063801 |
| 1.37000.5000 | 04054839369186 |
| 1.37000.1000 | 04054839369148 |
| 1.37000.9025 | 04027269061395 |