367982
2-Amino-5-fluorobenzoic acid
97%, for peptide synthesis
Synonym(s):
5-Fluoroanthranilic acid
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About This Item
Linear Formula:
H2NC6H3(F)CO2H
CAS Number:
Molecular Weight:
155.13
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
207-159-7
MDL number:
Beilstein/REAXYS Number:
2803664
Product Name
2-Amino-5-fluorobenzoic acid, 97%
InChI key
FPQMGQZTBWIHDN-UHFFFAOYSA-N
InChI
1S/C7H6FNO2/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H,10,11)
SMILES string
Nc1ccc(F)cc1C(O)=O
assay
97%
form
solid
reaction suitability
reaction type: solution phase peptide synthesis
Quality Level
application(s)
peptide synthesis
Application
Used in the synthesis of styrylquinazolinones which are potential anticancer agents.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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J B Jiang et al.
Journal of medicinal chemistry, 33(6), 1721-1728 (1990-06-01)
A novel series of 2-styrylquinazolin-4(3H-ones which inhibited tubulin polymerization and the growth of L1210 murine leukemia cells was discovered. Extensive structure-activity relationship studies suggest that the entire quinazolinone structure was required, but activity was further enhanced by halide or small
João Daniel Santos Fernandes et al.
PloS one, 10(7), e0132369-e0132369 (2015-07-15)
Metabolic diversity is an important factor during microbial adaptation to different environments. Among metabolic processes, amino acid biosynthesis has been demonstrated to be relevant for survival for many microbial pathogens, whereas the association between pathogenesis and amino acid uptake and
Marcela Briones-Martin-del-Campo et al.
Microbiology (Reading, England), 161(Pt 2), 300-310 (2014-12-07)
The fungal pathogen Candida glabrata has a well-defined oxidative stress response, is extremely resistant to oxidative stress and can survive inside phagocytic cells. In order to further our understanding of the oxidative stress response in C. glabrata, we characterized the
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