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Merck

96353

Kaempferol

analytical standard

Synonym(s):

3,4′,5,7-Tetrahydroxyflavone, 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, Robigenin

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About This Item

Empirical Formula (Hill Notation):
C15H10O6
CAS Number:
520-18-3
Molecular Weight:
286.24
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329770498
EC Number:
208-287-6
Beilstein/REAXYS Number:
304401
MDL number:
MFCD00016938

Key Documents

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Product Name

Kaempferol, analytical standard

InChI

1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H

InChI key

IYRMWMYZSQPJKC-UHFFFAOYSA-N

SMILES string

Oc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

grade

analytical standard

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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Related Categories

Application

Chromogenic reagent for antimony in the low ppm range and for gallium and indium in the sub-ppm range.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Potent inhibitor of osteoclastic bone resorption. The effect is believed to be attributable to both the antioxidant and estrogenic activities of kaempferol.

General description

Kaempferol is a bioflavonoid and a main component of the extract of Ginkgo biloba. It is also present in a variety of fruits and vegetables. It may serve as a potent candidate in the treatment of postmenopausal bone loss.

Other Notes

This compound is commonly found in plants of the genus: allium cinnamomum crataegus echinacea eucalyptus ginkgo glycyrrhiza hypericum lycium pimpinella primula sambucus

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

signalword

Warning

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

pictograms

Health hazardExclamation mark
GHS08,GHS07

Hazard Classifications

Eye Irrit. 2 - Muta. 2 - Skin Irrit. 2

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP3113
BCCM9040
BCCL8463
BCCK7289
BCCJ4507

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Drugs?Advances in Research and Application: 2012 Edition (2012)
Connective Tissue Cells: Advances in Research and Application: 2011 Edition (2012)
Avinash Kumar et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 82(3), 508-517 (2012-08-29)
A prototype formulation based on layer-by-layer (LbL) nano-matrix was developed to increase bioavailability of kaempferol with improved retention in bone marrow to achieve enhanced bone formation. The layer-by-layer nano-matrix was prepared by sequential adsorption of biocompatible polyelectrolytes over the preformed
Gil Fraqueza et al.
Dalton transactions (Cambridge, England : 2003), 41(41), 12749-12758 (2012-09-13)
Recently we demonstrated that the decavanadate (V(10)) ion is a stronger Ca(2+)-ATPase inhibitor than other oxometalates, such as the isoelectronic and isostructural decaniobate ion, and the tungstate and molybdate monomer ions, and that it binds to this protein with a
A Gohlke et al.
Journal of dairy science, 96(4), 2303-2313 (2013-02-14)
Because of their health-promoting properties, flavonoids are used in feed supplements for ruminants, although scientific evidence for their efficacy in vivo is limited. It has been shown recently that bioavailability of quercetin is low after ruminal administration in cows because
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