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Merck

537616

Diethylene glycol monoethyl ether

ReagentPlus®, 99%

Synonym(s):

2-(2-Ethoxyethoxy)ethanol, CARBITOL™, Diethylene glycol ethyl ether, Ethyldiglycol

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About This Item

Linear Formula:
C2H5OCH2CH2OCH2CH2OH
CAS Number:
111-90-0
Molecular Weight:
134.17
UNSPSC Code:
12352112
NACRES:
NA.21
PubChem Substance ID:
329757987
EC Number:
203-919-7
Beilstein/REAXYS Number:
1736441
MDL number:
MFCD00002872
Assay:
99%
Bp:
202 °C (lit.)
Vapor pressure:
0.12 mmHg ( 20 °C)

Key Documents

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Product Name

Diethylene glycol monoethyl ether, ReagentPlus®, 99%

InChI key

XXJWXESWEXIICW-UHFFFAOYSA-N

InChI

1S/C6H14O3/c1-2-8-5-6-9-4-3-7/h7H,2-6H2,1H3

SMILES string

CCOCCOCCO

vapor density

4.63 (vs air)

vapor pressure

0.12 mmHg ( 20 °C)

product line

ReagentPlus®

assay

99%

form

liquid

expl. lim.

1.2 %, 135 °F
23.5 %, 182 °F

dilution

(for general lab use)

refractive index

n20/D 1.427 (lit.)

bp

202 °C (lit.)

mp

-80 °C

solubility

water: soluble

density

0.999 g/mL at 25 °C (lit.)

Quality Level

100

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Application


  • A cautionary note on the effects of laboratory air contaminants on ambient ionization mass spectrometry measurements.: Highlights the influence of diethylene glycol monoethyl ether as a common laboratory contaminant that can affect the accuracy of mass spectrometry analyses, underscoring the importance of controlling environmental variables in high-precision analytical settings (Kumbhani SR et al., 2017).

General description

Diethylene glycol monoethyl ether (DEGMEE) is an organic solvent commonly used in the cosmetic industry. Its toxicity has been assessed. Various thermodynamic and optical parameters of an aqueous solution of DEGMEE have been determined. Its quantification along with diethylene glycol (DEG) and coumarin in food samples by gas chromatography-flame ionization technique has been reported.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
CARBITOL is a trademark of The Dow Chemical Company or an affiliated company of Dow

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

204.8 °F - closed cup

flash_point_c

96 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
0000507763
0000507763
0000480145
0000480145
MKCZ2384

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Thermodynamic and optical studies of some ethylene glycol ethers in aqueous solutions at T = 298.15 K.
Dhondge SS, et al.
The Journal of Chemical Thermodynamics, 41(5), 577-585 (2009)
Simultaneous determination of diethylene glycol, diethylene glycol monoethyl ether, coumarin and caffeine in food items by gas chromatography.
Rahim AA, et al.
Food Chemistry, 126(3), 1412-1416 (2011)
Reproductive toxicology. Diethylene glycol monoethyl ether.
Environmental health perspectives, 105 Suppl 1, 209-210 (1997-02-01)
Simona Mura et al.
Journal of drug targeting, 19(3), 189-196 (2010-05-08)
The aim of this work was to evaluate the ability of Transcutol (Trc) to produce elastic vesicles with soy lecithin (SL) and study the influence of the obtained vesicles on in vitro (trans)dermal delivery of minoxidil. To this purpose, so-called
Hyun-Jong Cho et al.
International journal of pharmaceutics, 423(2), 153-160 (2012-01-03)
To achieve rapid onset of action and improved bioavailability of udenafil, a microemulsion system was developed for its intranasal delivery. Phase behavior, particle size, transmission electron microscope (TEM) images, and the drug solubilization capacity of the microemulsion were investigated. A
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