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Merck

C0856

C7BzO

Synonym(s):

3-(4-Heptyl)phenyl-3-hydroxypropyl)dimethylammoniopropanesulfonate

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About This Item

Empirical Formula (Hill Notation):
C21H37NO4S
Molecular Weight:
399.59
NACRES:
NA.56
PubChem Substance ID:
24892277
UNSPSC Code:
12161902
MDL number:
MFCD04039997

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InChI

1S/C21H37NO4S/c1-4-5-6-7-8-10-19-11-13-20(14-12-19)21(23)15-17-22(2,3)16-9-18-27(24,25)26/h11-14,21,23H,4-10,15-18H2,1-3H3

SMILES string

CCCCCCCc1ccc(cc1)C(O)CC[N+](C)(C)CCCS([O-])(=O)=O

InChI key

FUPYROAFYPQUSH-UHFFFAOYSA-N

description

zwitterionic

assay

≥95.0% (HPLC)

form

solid

mol wt

399.59 Da (anhydrous)

aggregation number

≤25

technique(s)

dialysis: suitable, electrophoresis: suitable, protein quantification: suitable

Quality Level

200

Related Categories

General description

3-(4-heptyl)phenyl 3-hydroxypropyl dimethyl ammonio propane sulfonate (C7BzO) is a zwitterionic detergent comprising of a zwitterionic, hydrophilic head connected to the hydrophobic tail through a linker region. The prelinker region enhances detergent solubility. C7BzO is effective in sample preparation from plant membranes.

Application

C7BzO has been used as a component of extraction solution for protein isolation from mycelia and recombinant mammalian prion proteins.

Other Notes

Zwitterionic detergent; especially well-suited to protein extraction for proteomics applications.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000430892
SLCQ7604
0000430892
0000418190
0000418190

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Cristina-Maria Vâlcu et al.
Proteomics, 6(14), 4166-4175 (2006-06-23)
Protein extraction from plant samples is usually challenging due to the low protein content and high level of contaminants. Therefore, the 2-DE pattern resolution is strongly influenced by the procedure of sample preparation. Efficient solubilization of proteins strictly depends on
Gabriela Julia Golebiowska et al.
Acta biochimica Polonica, 66(3), 343-350 (2019-09-12)
Two winter triticale (x Triticosecale Wittmack) model cultivars: Hewo (tolerant to pink snow mould) and Magnat (sensitive) were used to test the effect of cold-hardening (4 weeks at 4°C) on soluble ≤50 kDa protein profiles of the seedling leaves. The
Structure-efficiency relationships of zwitterionic detergents as protein solubilizers in two-dimensional electrophoresis
Tastet C, et al.
Proteomics, 3(2), 111-121 (2003)
Improved high-yield expression, purification and refolding of recombinant mammalian prion proteins under aerosol-free elevated biological safety conditions
Rehbein P and Schwalbe H
Protein Expression and Purification, 150, 53-60 (2018)
Proteomic response of the biological control fungus Trichoderma atroviride to growth on the cell walls of Rhizoctonia solani
Grinyer J, et al.
Current Genetics, 47(6), 381-388 (2005)
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