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About This Item
Linear Formula:
HOOCCH(NH2)CH2CH2SCH2CH(NH2)COOH
CAS Number:
Molecular Weight:
222.26
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
208-613-7
MDL number:
Product Name
Cystathionine, ≥90% (HPLC)
InChI key
ILRYLPWNYFXEMH-UHFFFAOYSA-N
InChI
1S/C7H14N2O4S/c8-4(6(10)11)1-2-14-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)
SMILES string
NC(CCSCC(N)C(O)=O)C(O)=O
assay
≥90% (HPLC)
form
powder
color
white to off-white
mp
281 °C (dec.)
storage temp.
2-8°C
Quality Level
Gene Information
human ... BHMT(635)
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Related Categories
Biochem/physiol Actions
Cystathionine is an intermediate in the biosynthesis of the amino acid cysteine. Cystathionine is used as a substrate to differentiate and analyze cystathionine gamma-lyase(s).
Other Notes
A mixture of 4 stereoisomers; L-, D-, L-allo- and D-allo-cystathionine.
Preparation Note
Prepared by method of Stekol.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The Contribution of Homocysteine Metabolism Disruption to Endothelial Dysfunction: State-of-the-Art.
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Homocysteine (Hcy) is a sulfur-containing non-proteinogenic amino acid formed during the metabolism of the essential amino acid methionine. Hcy is considered a risk factor for atherosclerosis and cardiovascular disease (CVD), but the molecular basis of these associations remains elusive. The
Xu Cao et al.
Antioxidants & redox signaling, 31(1), 1-38 (2018-05-24)
Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous transmitter alongside nitric oxide and carbon monoxide. In
Qinghai Chen et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 49(6), 2200-2213 (2018-09-27)
The induction of excessive autophagy by increased levels of oxidative stress is one of the main mechanisms underlying unilateral ureteral obstruction (UUO)-induced vascular endothelial cell dysfunction. Hydrogen sulfide (H2S) has been shown to have an anti-oxidative effect, but its mode
Shuai Yuan et al.
Antioxidants & redox signaling, 27(10), 634-653 (2017-04-12)
Hydrogen sulfide (H In light of the recent understanding of oxidized sulfide metabolite formation and reactivity, comparatively few studies have been reported comparing cellular biological and in vivo effects of H Additional studies regarding persulfide and polysulfide formation and molecular
A new synthesis of S-(beta-amino-beta-carboxyethyl) homocysteine (cystathionine) and S-bis(gamma-amino-gamma -carboxypropyl) sulfide (homolanthionine).
J A STEKOL
The Journal of biological chemistry, 173(1), 153-157 (1948-03-01)
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