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SCC256

BPH-1 Human Benign Prostatic Hyperplasia Cell Line

The BPH-1 cell line is a well-established model for human prostate biology and widely used for investigation into the causes and potential treatments for prostatic disease.

Synonym(s):

BPH-1 cells, Benign Prostatic Hyperplasia cells

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About This Item

NACRES:
NA.81
UNSPSC Code:
41106514

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Product Name

BPH-1 Human Benign Prostatic Hyperplasia Cell Line, The BPH-1 cell line is a well-established model for human prostate biology and widely used for investigation into the causes and potential treatments for prostatic disease.

application(s)

cell analysis

Biochem/physiol Actions

Human, Epithelial Cells

Disclaimer

This product contains genetically modified organisms (GMO).
Within the EU GMOs are regulated by Directives 2001/18/EC and 2009/41/EC of the European Parliament and of the Council and their national implementation in the member States respectively. Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

BPH-1 is an immortalized benign prostatic hyperplasia cell line that is a highly cited human model for prostate growth and physiology. Compared to prostate cancer cell lines, BPH-1 cells expressed increased levels of estradiol (E2) and aromatase, factors that have been implicated in BPH progression (2). BPH-1 cells share the cytokeratin profile of luminal epithelial cells and do not express androgen receptor or prostate-specific antigen (PSA) (3). BPH-1 cells express the proto-oncogene p53 and harbor several chromosomal structural rearrangements but are non-tumorigenic in nude mice (3). Source:The BPH-1 cell line was established from primary prostatic tissue from a 68-year-old patient and the cell line was immortalized with Simian virus 40 (SV40) large T antigen (3). BPH-1 cells contain a neomycin resistance cassette and are resistant to G418.

Other Notes

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact licensing@emdmillipore.com.

Packaging

≥1X106 cells/vial

Preparation Note

Store in liquid nitrogen. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

SCC256:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
SCC25604061841079835

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