Skip to Content
Merck

5.05026

DNQX Disodium Salt

Synonym(s):

DNQX Disodium Salt, AMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C8H2N4Na2O6
CAS Number:
2379-57-9
Molecular Weight:
296.10
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD00069257

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

SMILES string

[N+](=O)([O-])c1cc2[nH][c]([c]([nH]c2cc1[N+](=O)[O-])=O)=O

InChI

1S/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14)

InChI key

RWVIMCIPOAXUDG-UHFFFAOYSA-N

assay

≥99% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

dark brown

solubility

H2O: 100 mM

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

Primary Target
AMPA
Secondary Target
GluK2
Target IC50: 0.19 to 1.66 uM

Disclaimer

Toxicity: Standard Handling (A)

General description

A potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66 µM and 0.35 µM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate and NMDA receptors in studying brain functions and disorders.

Other Notes

Lee, S., et al. 2010. J. Neurophysiol.103, 1728.
Honor, T., et al. 1998. Science.241, 701.
Watkins, J., et al. 1990. Adv. Exp. Med. Biol.268, 49.
Davies, S., et al. 1990. Int. Rev. Neurobiol.32, 28.

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
5.05026.000104055977263336

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service