335452
Lithium (trimethylsilyl)acetylide solution
0.5 M in THF
Synonym(s):
(Trimethylsilyl)ethynyllithium
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About This Item
form
liquid
Quality Segment
concentration
0.5 M in THF
density
0.88 g/mL at 25 °C
SMILES string
[Li]C#C[Si](C)(C)C
InChI
1S/C5H9Si.Li/c1-5-6(2,3)4;/h2-4H3;
InChI key
ZVXXEONXFWSCIZ-UHFFFAOYSA-N
Application
- In the transmetalation and nucleophilic displacement reactions.
- To prepare propargylic alcohol derivatives by reacting with aldehydes and ketones.
- To synthesize α,βynones by treating with Weinreb amide or with isoxazolidide.
- Along with Grignard reagent to convert γ- and δ-thiolactams to thioiminium salts, which are employed as key intermediates to produce disubstituted pyrrolidines.
Packaging
Legal Information
Signal Word
Danger
Hazard Codes
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1B - STOT SE 3
Target Organs
Central nervous system, Respiratory system
supp_hazards
Storage Class
3 - Flammable liquids
Flash Point (°F)
-9.4 °F - closed cup
Flash Point (°C)
-23 °C - closed cup
PPE (personal protective equipment)
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Regulatory Listings
Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.
Class I Designated Chemical Substances
prtr
Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water insoluble liquid
fsl
Substances Subject to be Indicated Names
ishl_indicated
Substances Subject to be Notified Names
ishl_notified
335452-BULK: + 335452-50ML:4548173136639 + 335452-500ML:4548173136622 + 335452-4X25ML: + 335452-VAR:
jan
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