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Merck

412368

PAMAM dendrimer

ethylenediamine core, generation 0.0 solution, 20 wt. % in methanol

Synonym(s):

Poly(amidoamine)

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About This Item

Linear Formula:
NH2(CH2)2NH2]:(G=0);dendri PAMAM(NH2)4
CAS Number:
Molecular Weight:
516.68
NACRES:
NA.23
PubChem Substance ID:
UNSPSC Code:
12162002
MDL number:
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description

amino surface groups

Quality Segment

form

liquid

mol wt

generation 0.0

feature

core type ethylenediamine core (2-carbon core)

concentration

20 wt. % in methanol

no. Surface Groups

4

refractive index

n20/D 1.364

bp

64.7 °C

density

0.854 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

NCCNC(=O)CCN(CCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN

InChI

1S/C22H48N10O4/c23-5-9-27-19(33)1-13-31(14-2-20(34)28-10-6-24)17-18-32(15-3-21(35)29-11-7-25)16-4-22(36)30-12-8-26/h1-18,23-26H2,(H,27,33)(H,28,34)(H,29,35)(H,30,36)

InChI key

SENLDUJVTGGYIH-UHFFFAOYSA-N

General description

PAMAM dendrimer is a poly(amidoamine) that is categorized under the class of dendritic polymers, which can be prepared by a two-step reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular branched upon branched pattern. PAMAM is majorly used as a high capacity chelating agent.

Application

PAMAM dendrimer belongs to the family of dendrimers, which can be used in biomedical and drug delivery applications.

Physical form

Contains 4 surface primary amino groups

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

412368-5G:4.54817314713E12 + 412368-25G:4.548173147123E12

jan



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