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412422

PAMAM dendrimer, ethylenediamine core, generation 3.0 solution

20 wt. % in methanol

Synonym(s):

Starburst PAMAM-G 3

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About This Item

Linear Formula:
[NH2(CH2)2NH2]:(G=3);dendri PAMAM(NH2)32
CAS Number:
153891-46-4
Molecular Weight:
6908.84
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00197936
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description

amino surface groups

Quality Segment

100

form

liquid

mol wt

generation 3.0

feature

core type ethylenediamine core (2-carbon core)

concentration

20 wt. % in methanol

no. Surface Groups

32

refractive index

n20/D 1.367

bp

64.7 °C

density

0.863 g/mL at 25 °C

storage temp.

2-8°C

General description

PAMAM dendrimer is a symmetrical polymer with a large number of terminal groups that can easily bind to biomolecules due to their biocompatibility and affinity. These dendrimers have a multivalent surface that contains envelopes and various active sites at the core with the attached dendrons. They are highly branched nanoscale polymers that are extensively used in the field of biomedicine for targeted drug delivery.

Application

PAMAM dendrimers can be used as transfection agents for the delivery of nucleic acids. For example, it can be used in the pulmonary delivery of siRNA directed against tumor necrosis factor (TNF).

Physical form

Contains 32 surface primary amino groups

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

412422-25G:4.548173147246E12 + 412422-5G:4.548173147253E12

jan

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