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536709

PAMAM dendrimer, ethylenediamine core, generation 5.0 solution

5 wt. % in methanol

Synonym(s):

Poly(amidoamine)

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About This Item

Linear Formula:
[NH2(CH2)2NH2]:(G=5);dendri PAMAM(NH2)128
CAS Number:
163442-68-0
Molecular Weight:
28824.81
UNSPSC Code:
12162002
NACRES:
NA.23
MDL number:
MFCD00197936
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description

amino surface groups

Quality Segment

100

form

liquid

mol wt

generation 5.0

feature

core type ethylenediamine core (2-carbon core)

concentration

5 wt. % in methanol

no. Surface Groups

128

density

0.797 g/mL at 25 °C

storage temp.

2-8°C

General description

PAMAM dendrimers are water-soluble, non-immunogenic, and biocompatible symmetrical polymers. They possess a large quantity of modifiable terminal functional groups that can bind to various targeting or guest molecules. These terminal groups are used to covalently attach drugs, targeting ligands, or imaging agents for targeted delivery, controlled release, or imaging applications.

Application


  • Synthesis of beta-Cyclodextrin-Decorated Dendritic Compounds Based on EDTA Core: This study presents an alternative to the ethylenediamine core in PAMAM dendrimers, using an EDTA core instead, providing insights into modifications that affect the dendrimers properties (Gonzalez Mendez et al., 2022).

  • New Advances in General Biomedical Applications of PAMAM Dendrimers: Discusses the composition variations of PAMAM dendrimer cores, including ethylenediamine, and their implications on biomedical applications (Araujo et al., 2018).

  • Poly (amidoamine) Dendrimers: Covalent and Supramolecular Synthesis: This paper reviews various synthetic strategies for PAMAM dendrimers, emphasizing the role of the ethylenediamine core in their structural formation (Lyu et al., 2019).

  • Modified Carboxyl-Terminated PAMAM Dendrimers as a Cytocompatible Nano Based Drug Delivery System: Examines the biocompatibility and drug delivery efficiency of modified PAMAM dendrimers, highlighting the cores critical role (Vu et al., 2019).

  • Use of Polyaminoamide Dendrimers Starting from Different Core-Initial Molecules for Inhibition of Silica Scale: This study explores the use of ethylenediamine-core PAMAM dendrimers in industrial applications, particularly for silica scale inhibition (Sun et al., 2021).

Physical form

Contains 128 surface primary amino groups.

Legal Information

Manufactured by Dendritech®, Inc.
Dendritech is a registered trademark of Dendritech, Inc.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

49.5 °F - closed cup - Methanol

flash_point_c

9.7 °C - closed cup - Methanol

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Alcohols + Hazardous rank II

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

536709-5G:4.548173167428E12

jan

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