Skip to Content
Merck

Key Documents

View All Documentation

731013

JackiePhos

95%, solid

Synonym(s):

2-{Bis[3,5-bis(trifluoromethyl)phenyl]phosphino}-3,6-dimethoxy -2′,4′,6′-triisopropyl-1,1′-biphenyl, Bis(3,5-bis(trifluoromethyl)phenyl)(2′,4′,6′- triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C39H37F12O2P
CAS Number:
1160861-60-8
Molecular Weight:
796.66
UNSPSC Code:
12352112
PubChem Substance ID:
329764613
NACRES:
NA.22
MDL number:
MFCD17015286
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

JackiePhos, 95%

Quality Segment

100

product line

Buchwald Ligand

assay

95%

form

solid

reaction suitability

reaction type: Cross Couplings, reagent type: ligand
reaction type: Buchwald-Hartwig Cross Coupling Reaction, reagent type: ligand
reaction type: C-X Bond Formation

mp

186-190 °C

functional group

phosphine

SMILES string

COc1ccc(OC)c(c1P(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F)-c4c(cc(cc4C(C)C)C(C)C)C(C)C

InChI

1S/C39H37F12O2P/c1-19(2)22-11-29(20(3)4)33(30(12-22)21(5)6)34-31(52-7)9-10-32(53-8)35(34)54(27-15-23(36(40,41)42)13-24(16-27)37(43,44)45)28-17-25(38(46,47)48)14-26(18-28)39(49,50)51/h9-21H,1-8H3

InChI key

KYTUFIMHJNRPLC-UHFFFAOYSA-N

Application

Catalyst for N-Arylation reactions

Buchwald Phosphine Ligands for chemical Synthesis
JackiePhos is a Buchwald′s phosphine ligand which can be used for the:
  • glycosyl cross-coupling reaction of diaryliodonium triflates with anomeric stannanes to synthesize C-glycosides.
  • synthesis of gold-based catalyst complexes such as [Au(CH3CN)(JackiePhos)][SbF6] and [(JackiePhos)AuCl.
  • acylation of alkylcarbastannatranes.
  • synthesis of cyclic guanidines or cyclic ureas bearing dialkylaminomethyl groups in combination with Pd(acac)2 as a catalyst.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library