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1.13364

Tetrahydrofuran-d8

deuteration degree min 99.5% for NMR spectroscopy MagniSolv™

Synonym(s):

THF deuterated, Deuterated tetrahydrofuran, Octadeuterotetrahydrofuran

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About This Item

Linear Formula:
(CD2)4O
CAS Number:
1693-74-9
Molecular Weight:
80.16
UNSPSC Code:
12142201
NACRES:
NA.22
EC Index Number:
216-898-4
MDL number:
MFCD00044238
Beilstein/REAXYS Number:
111854
Mass shift:
M+8
Form:
liquid
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Quality Segment

200

form

liquid

autoignition temp.

215 °C

potency

1650 mg/kg LD50, oral (Rat)

technique(s)

NMR: suitable

impurities

≤0.030% Water (H<SUB>2</SUB>O) (NMR), ≤0.050% Water (H<SUB>2</SUB>O) (Karl Fischer)

refractive index

n20/D 1.403 (lit.)

bp

65-66 °C (lit.)

mp

−106 °C (lit.)

transition temp

flash point -17.5 °C

density

0.985 g/mL at 25 °C (lit.)

mass shift

M+8

storage temp.

2-8°C

SMILES string

[2H]C1([2H])OC([2H])([2H])C([2H])([2H])C1([2H])[2H]

InChI

1S/C4H8O/c1-2-4-5-3-1/h1-4H2/i1D2,2D2,3D2,4D2

InChI key

WYURNTSHIVDZCO-SVYQBANQSA-N

General description

A wide range of MagniSolv deuterated solvents with extremely low residual water, excellent chemical purity, and the highest isotopic enrichment available can satisfy the most demanding requirements of researchers. Depending on application and sensitivity of the NMR spectrometer our offer solvents with deuteration degrees between 98% and 99.96%. In case of all the water soluble deuterated standard products, water content is specified according to both Karl Fischer and NMR.

Application


  • Experimental and Theoretical Study of CO2 Insertion into Ruthenium Hydride Complexes.: This research provides insights into the mechanistic pathways for CO2 reactivity with ruthenium hydride complexes, potentially relevant for catalytic applications including transformations involving Tetrahydrofuran-d₈ (Ramakrishnan et al., 2016).


  • Syntheses, structures, and NMR chemical shifts of a family of trimethyltin alkoxide, amide, halide and cyclopentadienyl compounds.: Details the synthesis and structural characterization of trimethyltin compounds, useful for understanding the coordination chemistry that may involve Tetrahydrofuran-d₈ as a solvent or structural analogue (Lichtscheidl et al., 2015).


  • NMR studies of coupled low- and high-barrier hydrogen bonds in pyridoxal-5′-phosphate model systems in polar solution.: Discusses the application of NMR spectroscopy in studying hydrogen bonding interactions, where Tetrahydrofuran-d₈ could be utilized as a deuterated solvent for enhanced spectral clarity (Sharif et al., 2007).


  • Stable hydrocarbon diradical, an analogue of trimethylenemethane.: Investigates stable hydrocarbon diradicals, where Tetrahydrofuran-d₈ may be used as part of the experimental setup to stabilize reactive intermediates or as a solvent to study radical stability (Rajca et al., 2005).


Analysis Note

Deuteration degree: ≥ 99.50 %
Water (NMR, H₂O): ≤ 0.030 %
Performance test (NMR-spectrum): passes test
Water (K. Fischer, H₂O + D₂O): ≤ 0.050 %

Other Notes

Check out ChemisTwin®, our brand new online portal for identity confirmation and quantification of NMR spectra. Learn more or reach out to us for a free trial.

Legal Information

MAGNISOLV is a trademark of Merck KGaA, Darmstadt, Germany

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signalword

Danger

supp_hazards

EUH019

Storage Class

3 - Flammable liquids

flash_point_f

1.4 °F - closed cup

flash_point_c

-17 °C - closed cup

target_organs

Central nervous system, Respiratory system

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

Class I Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water soluble liquid

fsl

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