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Merck

8.00683

Succinic anhydride

for synthesis

Synonym(s):

Succinic anhydride

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About This Item

Empirical Formula (Hill Notation):
C4H4O3
CAS Number:
108-30-5
Molecular Weight:
100.07
UNSPSC Code:
12352115
EC Index Number:
203-570-0
NACRES:
NA.22
MDL number:
MFCD00005525

Key Documents

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SMILES string

O1C(=O)CCC1=O

InChI

1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2

InChI key

RINCXYDBBGOEEQ-UHFFFAOYSA-N

vapor pressure

1.3 hPa ( 92 °C)

form

crystals

autoignition temp.

480 °C

potency

1510 mg/kg LD50, oral (Rat)

pH

2.7 (10 g/L in H2O)

bp

261 °C/1013 hPa

mp

116-120 °C

transition temp

flash point 157 °C

solubility

62.9 g/L (Hydrolysis)

density

1.23 g/cm3 at 20 °C

bulk density

550‑600 kg/m3

storage temp.

2-30°C

Quality Level

200

Application

  • Enhanced antimicrobial fibers: Succinic anhydride is utilized in the conjugation of chitosan with Harakeke and Hemp fibers to produce antimicrobial fibers, which significantly increase their utility in medical and hygiene products (Barker et al., 2024).
  • Antitumor diterpenoids: Succinic anhydride is integral to synthesizing new clerodane diterpenoids from Callicarpa pseudorubella, which show potential antitumor proliferative activity, expanding its applications in cancer research (Pan et al., 2024).
  • Nanogel delivery systems: It plays a role in developing nanogel delivery systems for cationic peptides, enhancing the delivery of therapeutic agents and showcasing its versatility in pharmaceutical delivery systems (Mørck Nielsen et al., 2024).

Analysis Note

Assay (morpholine method): ≥ 98,0 %(m)
Identity (IR): conforms
Melting range (lower value): ≥ 116 °C
Melting range (upper value): ≤ 120 °C

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

Storage Class

8A - Combustible, corrosive hazardous materials

wgk

WGK 1

flash_point_f

314.6 °F

flash_point_c

157 °C

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

Certificates of Analysis (COA)

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Ananthakrishnan Soundaram Jeevarathinam et al.
Angewandte Chemie (International ed. in English) (2019-12-17)
We report a new approach to monitor drug release from nanocarriers via a paclitaxel-methylene blue conjugate (PTX-MB) with redox activity. This construct is in a photoacoustically silent reduced state inside poly(lactic-co-glycolic acid) (PLGA) nanoparticles (PTX-MB@PLGA NPs). During release, PTX-MB is

Global Trade Item Number

SKUGTIN
8.00683.050004022536361840
8.00683.100004022536361857
8.00683.010004022536361833
8.00683.905004022536361864

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