Skip to Content
Merck

8.22184

TWEEN® 20

for synthesis

Synonym(s):

Montanox 20, Polyoxyethylene (20) sorbitan monolaurate, Polysorbate 20, Polyethylene glycol sorbitan monolaurate, Polyoxyethylenesorbitan monolaurate

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

CAS Number:
9005-64-5
NACRES:
NA.22
EC Index Number:
500-018-3
UNSPSC Code:
12352104
MDL number:
MFCD00165986

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

vapor pressure

<1.4 hPa ( 20 °C)

form

liquid

potency

38900 mg/kg LD50, oral (Rat)

Quality Level

200

refractive index

n20/D 1.468 (lit.)

pH

6-8 (20 °C, 50 g/L in H2O)

transition temp

flash point 275 °C

storage temp.

2-30°C

Looking for similar products? Visit Product Comparison Guide

General description

Tween®-20 is a polysorbate-based non-ionic surfactant. It is made up of three chemical units:
  • aliphatic ester chains that hinder biomolecules from nonspecific interactions
  • aliphatic chain that can be non-covalently adsorbed on a hydrophobic surface
  • hydrophilic terminal hydroxyl groups, which can be chemically modified for potential applications.

Application

Non-ionic detergent
Tween®-20 can be used as a structure-directing agent in the preparation of mesoporous oxide films because of its ability to promote textural properties of the films such as controllable crystallinity, film morphology, tailor-designed pore structure, high BET surface area, and controlled film thickness. It is also used in the synthesis of AuNPs/TWEEN/GO composites, where Tween®-20 acts as a reducing and immobilizing agent for AuNPs (Au nanoparticles) as well as a stabilizing agent for GO (graphene oxide).
Tween®-20 can also be used as an emulsifying, solubilizing, and wetting agent in a variety of liquid formulations.

Analysis Note

Density (d 20 °C/ 4 °C): 1.095 - 1.105
Hydroxyl value: 96 - 108
Saponification value: 40 - 50
Identity (IR): passes test
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

flash_point_f

527.0 °F - Pensky-Martens closed cup

flash_point_c

275 °C - Pensky-Martens closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

8221842501: + IN2RCMT822184: + 8221842521: + 8221842500: + 8221840500: + 8221849999: + 8221840000: + 8221840521: + 8221849027: + 8221841000: + 8221840501: + 8221840050:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Relationships between the hydrophilic-lipophilic balance values of pharmaceutical excipients and their multidrug resistance modulating effect in Caco-2 cells and rat intestines
Lo Yu-li
Journal of Controlled Release : Official Journal of the Controlled Release Society, 90(1), 37-48 (2003)
Synthesis, characterization and electrochemical properties of mesoporous zirconia nanomaterials prepared by self-assembling sol-gel method with Tween 20 as a template
Chen Y, et al.
Chemical Engineering Journal, 170(2-3), 518-524 (2011)
Development and evaluation of solid self nano-emulsifying formulation of rosuvastatin calcium for improved bioavailability
Kulkarni NS, et al.
Tropical Journal of Pharmaceutical Research, 14(4), 575-582 (2015)
Mass transport phenomena in oil-in-water emulsions containing surfactant micelles: Ostwald ripening
Weiss J, et al.
Langmuir, 16(17), 6833-6838 (2000)
Hierarchical macro-mesoporous structures in the system TiO2-Al2O3, obtained by hydrothermal synthesis using Tween-20 as a directing agent
Garcia-Benjume ML, et al.
Materials Characterization, 60(12), 1482-1488 (2009)
View All Related Papers

Global Trade Item Number

SKUGTIN
8.22184.100004022536485652
8.22184.050004022536485645
8.22184.250004022536685243

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service