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Merck

8.43942

Propanephosphonic acid anhydride

(50% solution in ethyl acetate) for synthesis T3P

Synonym(s):

2,4,6-Tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide solution, PPACA, Propylphosphonic anhydride, T3P

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About This Item

NACRES:
NA.22
UNSPSC Code:
12352108
Form:
liquid
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vapor pressure

97 hPa ( 20 °C)

Quality Segment

form

liquid

bp

77 °C/1013 hPa (ethyl acetate)

transition temp

flash point -4 °C (ethyl acetate)

density

1.08 g/cm3 at 20 °C

storage temp.

2-8°C

Application

  • Cyclization of Linear Tetrapeptides Containing N‐Methylated Amino Acids: The study reports the synthesis of naturally occurring cyclotetrapeptides using 1-propanephosphonic acid anhydride, noting unexpected findings in cyclization patterns. (Zhang et al., 2017).

Analysis Note

Assay (T3P) (NMR): ≥ 40.0 %
Pyropropanephosphonic acid (NMR): ≤ 10.0 %
Propanephosphonic acid (NMR): ≤ 0.50 %
Ethyl acetate (calculated): ≤ 50.0 %


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signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

24.8 °F - closed cup - ethyl acetate

flash_point_c

-4 °C - closed cup - ethyl acetate


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

8439420050: + 8439420000: + 8439420100: + 8439429999: + 8439422500: + 8439420025:

jan

Group 4: Flammable liquids + Type 1 petroleums + Hazardous rank II + Water insoluble liquid

fsl



Certificates of Analysis (COA)

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