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Merck

MAB5228

Anti-Amyloid Precursor Protein (APP) Antibody

CHEMICON®, mouse monoclonal, OM84

Synonym(s):

APP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
OM84, monoclonal
Species reactivity:
human
Application:
ELISA, WB
Citations:
3

Key Documents

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Product Name

Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84, clone OM84, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

OM84, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, western blot: suitable

isotype

IgG2aκ

NCBI accession no.

NM_000484.2, NM_201413.1, NM_201414.1

UniProt accession no.

P05067

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... APP(351)

Immunogen

Amyloid Precursor Protein (APP) secreted by the EJ-1 bladder carcinoma cell line.
Epitope: Secretory

Application

Anti-Amyloid Precursor Protein Antibody, Secretory, clone OM84 detects level of Amyloid Precursor Protein & has been published & validated for use in ELISA & WB.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Western blot: 10 μg/mL ELISA: 1 μg/mL

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with secretory amyloid precursor protein (sAPP), but not with Amyloid-Beta protein 1-40.

Physical form

Format: Purified
Protein A Purified mouse immunoglobulin in 10 mM sodium phosphate buffer (pH 7.4), 0.15 M NaCl, and 0.1% sodium azide as a preservative..
Protein A purified

Preparation Note

Maintain frozen at -70°C or below in undiluted aliquots for up to 12 months, avoid repeated freeze/thaw cycles.

Analysis Note

Control
Brain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

MAB5228:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Christine Römer et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(20), 7777-7794 (2015-05-23)
Stroke-induced immunodepression (SIDS) is an essential cause of poststroke infections. Pharmacological inhibition of SIDS appears promising in preventing life-threatening infections in stroke patients. However, SIDS might represent an adaptive mechanism preventing autoreactive immune responses after stroke. To address this, we

Global Trade Item Number

SKUGTIN
MAB522804053252501852

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