Skip to Content
Merck

Key Documents

View All Documentation

HCD8MAG15KPX17BK

MILLIPLEX® Human CD8+ T Cell Panel

Bulk (Space Saver) Premixed Human CD8+ T Cell 17-Plex Panel

Synonym(s):

17-Plex CD8+ T Cell Panel, 17-Plex Magnetic Bead Panel, CD8+ T Cell Magnetic Bead Panel, Human CD8 T cell cytokine panel, Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

UNSPSC Code:
12161503
NACRES:
NA.47
eCl@ss:
32161000
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

MILLIPLEX® Human CD8+ T Cell Panel,

Quality Segment

200

description

Bulk (Space Saver) Premixed Human CD8+ T Cell 17-Plex Panel

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

standard curve range: 0.4-1,500 pg/mL
(IL-6), standard curve range: 0.5-2,000 pg/mL
(TNFα), standard curve range: 1-3,500 pg/mL
(MIP-1α), standard curve range: 1-5,000 pg/mL
(Granzyme B), standard curve range: 1-5,000 pg/mL
(IFNγ), standard curve range: 1-5,000 pg/mL
(IL-5), standard curve range: 10-50,000 pg/mL
(Perforin), standard curve range: 10-50,000 pg/mL
(sFasL), standard curve range: 2-10,000 pg/mL
(IL-4), standard curve range: 2-10,000 pg/mL
(sCD137), standard curve range: 2-7,500 pg/mL
(IL-13), standard curve range: 2-7,500 pg/mL
(IL-2), standard curve range: 20-100,000 pg/mL
(Granzyme A), standard curve range: 4-15,000 pg/mL
(GM-CSF), standard curve range: 400-1,650,000 pg/mL
(sFas), standard curve range: 5-20,000 pg/mL
(IL-10), standard curve range: 7-30,000 pg/mL
(MIP-1β)

technique(s)

multiplexing: suitable

input

plasma
cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

CD8+ T cells (also known as cytotoxic T cells, cytolytic T cells and killer T cells) belong to a sub-group of T cells capable of inducing the death of infected somatic or tumor cells. T cells that bind weakly to Major Histocompatibility Complex (MHC) self-antigens are positively selected into single-positive CD4+ or CD8+ T cells in the thymus. Those CD8+ T cells that survive and mature after activation become cytotoxic cells, expressing T-cell receptors (TCRs) capable of recognizing specific antigenic peptides bound to Class I MHC molecules and the glycoprotein CD8. Affinity between the CD8 protein and the MHC molecule helps to keep the cytotoxic T cell and target closely bound during antigen specific activation. Once activated, CD8+ T cells are generally classified as having a predefined cytotoxic role within the immune system and undergo IL-2 induced clonal expansion, which increases the number of cells specific for the target antigen. The CD8+ T cells then travel throughout the body in search of antigen-positive somatic/tumor cells.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 17 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: GM-CSF, sCD137, IFNγ, sFas, sFasL, Granzyme A, Granzyme B, IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, MIP-1α, MIP-1β, TNF-α, Perforin

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Broad Analyte Array: This multiplex assay includes 15 essential analytes that play a role in CD8+ T cell function, such as GM-CSF, IFNγ, IL-2, Granzyme A, and Perforin, enabling comprehensive immune response studies.
  • Deep Insights into Immune Function: Measuring multiple cytokines and chemokines linked to CD8+ T cell activity enhances understanding of the immune response in various diseases, including infections and cancers.
  • Bulk Space Saver Packaging: The bulk packaging option is designed to conserve laboratory space and reduce waste, making it a cost-effective solution for high-volume laboratories while maintaining the integrity of the reagents.
  • Boosted Laboratory Productivity: The multiplex format increases throughput, allowing for the analysis of more samples in less time, which is essential for high-throughput research settings.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Still not finding the right product?

Explore all of our products under MILLIPLEX® Human CD8+ T Cell Panel

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Please refer to KIT Component information

pdsc

Please refer to KIT Component information

prtr

Please refer to KIT Component information

fsl

Please refer to KIT Component information

ishl_indicated

Please refer to KIT Component information

ishl_notified

Please refer to KIT Component information

cart

キットコンポーネントの情報を参照してください

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library