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HCY4MG-64K-PX20

MILLIPLEX® Human Cytokine/Chemokine Panel 4

Premixed Human Cytokine/Chemokine 20-Plex Panel 4

Synonym(s):

Human Cytokine Panel

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161503
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Product Name

MILLIPLEX® Human Cytokine/Chemokine Panel 4,

description

Premixed Human Cytokine/Chemokine 20-Plex Panel 4

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

serum
cell culture supernatant(s)
plasma

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

“Cytokine” is a general term used for a diverse group of soluble proteins and peptides which act as regulators under both normal and pathological conditions to modulate the functional activities of individual cells and tissues. These proteins also mediate direct interactions between cells and regulate processes taking place in the extracellular environment. The cytokine group of proteins includes lymphokines, interferons, colony stimulating factors and chemokines. Cytokine and chemokine research plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, as well as disease states such as inflammatory disease, allergic reactions, irritable bowel disease (IBD), sepsis, and cancer.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 20 analytes in human serum, plasma, and cell culture supernatants.

Analytes included: BAFF/Blys, BRAK/CXCL14, CCL28, CXCL16, HCC-4/CCL16, HMGB1, IFNβ, IL-14, IL-19, IL-24, IL-28B, IL-32α, IL-34, IL-35, IL-36β/IL-1F8, IL-37/IL-1F7, IL-38/IL-1F10, MIP-4, MPIF/CCL23, YKL40

Note: HMGB1 can be measured in serum and plasma samples only.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

  • Translational Versatility: Profile understudied mediators like IL-19 (skin inflammation), IL-28B (IFN-gamma3), and MPIF/CCL23 (angiogenesis) to explore their roles in niche therapeutic areas, from dermatology to viral hepatitis.
  • Key Innovations: First multiplex panel to combine IL-37, IL-38, and IL-35—critical for studying resolution of inflammation.
  • Parallel Analysis: Measure damage-associated (HMGB1) and regulatory (IL-35) signals in trauma or chronic disease.
  • Cross-Disciplinary Utility: From viral immunology (IL-28B) to neuroinflammation (IL-19), address diverse therapeutic areas.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

10 - Combustible liquids

wgk

WGK 3

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Please refer to KIT Component information

pdsc

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prtr

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fsl

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ishl_indicated

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ishl_notified

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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