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HNDGAB-220K

MILLIPLEX® Human Neurodegenerative Autoantibody Magnetic Bead Panel

Simultaneously analyze up to 25 autoantibodies in a bead-based assay using Luminex technology, in human serum, plasma, and cerebrospinal fluid (CSF)

Synonym(s):

Luminex® neuro autoantibody assay, Luminex® neurodegenerative autoantibody assay, Millipore neuro autoantibody panel, Millipore neurodegenerative autoantibody panel, neuro autoantibody kit, neuro autoantibody multiplex kit, neurodegenerative autoantibody kit

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About This Item

UNSPSC Code:
41116126
NACRES:
NA.84

Product Name

MILLIPLEX® Human Neurodegenerative Autoantibody Magnetic Bead Panel,

Quality Segment

200

description

Simultaneously analyze up to 25 autoantibodies in a bead-based assay using Luminex® technology, in human serum, plasma, and cerebrospinal fluid (CSF)

product line

Milliplex®

quality

200

species reactivity

human

technique(s)

multiplexing: suitable

input

serum
plasma

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

General description

Neurodegenerative autoantibodies are immune system-produced antibodies that mistakenly attack the body′s own nervous system proteins, disrupting synaptic function and causing inflammation and neuronal damage. They target essential proteins like synaptic proteins, neuronal antigens, cell surface receptors, and aggregation-prone proteins. Detecting these autoantibodies in blood or cerebrospinal fluid (CSF) can provide valuable insights into the autoimmune processes linked to neurodegenerative diseases. Research on autoantibodies enhances our understanding of serious neurological disorders and may lead to new therapeutic options.

Application

MILLIPLEX® Qualified assays undergo rigourous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 25 neurodegenerative autoantibodies in human serum, plasma, and CSF.

Analytes included: anti-α-synuclein, anti-AChR (acetylcholine receptor), anti-AGNA (Anti-Glial Nuclear Antibody, SOX1), anti-Ago2 (Su), anti-CRYAB (α B-crystallin), anti-AMPA-R, anti-Amphiphysin, anti-ANNA2 (Ri)/NOVA1, anti-AQP4 (aquaporin-4), anti-Aβ42, anti-CRMP5 (Collapsin Response Mediater Protein 5), anti-DPPX, anti-DRD2 (Dopamine D2 Receptor), anti-ELAVL4 (HuD), anti-GFAP (Glial Fibrillary Acidic Protein), anti-MBP (Myelin Basic Protein), anti-C1q, anti-mGluR1, anti-MOG (Myelin Oligodendrocyte Glycoprotein), anti-NF-L (Neurofilament light chain), anti-NMDAR1, anti-NRXN3 (neurexin-3), anti-PCA1 (Yo)/CDR2, anti-PNMA1 (Ma1), and anti-tTau

Assay Characteristics: Refer to kit protocol for assay cross-reactivity and sensitivity.

Features and Benefits

  • Versatile Analyte Selection: Customize your research with the ability to select from a panel of 25 neurodegenerative autoantibodies, allowing for tailored solutions that address specific research questions.
  • All-in-One Kit Format: Each kit includes all necessary reagents and an intuitive protocol, simplifying the assay process and reducing the need for multiple kits, which saves time and resources.
  • High Precision and Specificity: Achieve reliable results with demonstrated precision (<10% intra-assay CV and <15% inter-assay CV) and minimal cross-reactivity, ensuring the accuracy and trustworthiness of your findings.
  • Unique Neurodegenerative Disease Research Tool: This first-of-its-kind assay enables valuable insights into the autoimmune mechanisms underlying neurodegenerative diseases.

Preparation Note

Recommended storage for kit components is 2-8˚C.

Legal Information

Luminex is a registered trademark of Luminex Corporation
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

pictograms

Exclamation markEnvironment
GHS07,GHS09

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Warning

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

10 - Combustible liquids

flash_point_f

No data available

flash_point_c

No data available

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Please refer to KIT Component information

pdsc

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prtr

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fsl

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ishl_indicated

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ishl_notified

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キットコンポーネントの情報を参照してください

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