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MAB1645

Anti-Dystrophin Antibody

CHEMICON®, mouse monoclonal, 1808

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
1808, monoclonal
Species reactivity:
chicken, mouse, rat, human
Application:
IHC, WB
Citations:
11
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Product Name

Anti-Dystrophin Antibody, clone 1808, clone 1808, Chemicon®, from mouse

biological source

mouse

Quality Segment

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

1808, monoclonal

species reactivity

chicken, mouse, rat, human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000109.2, NM_004006.1, NM_004007.1, NM_004009.2, NM_004010.2, NM_004011.2, NM_004012.2, NM_004013.1, NM_004014.1, NM_004015.1, NM_004016.1, NM_004017.1, NM_004018.1, NM_004019.2, NM_004020.1, NM_004021.1, NM_004022.1, NM_004023.1

UniProt accession no.

P11532

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... DMD(1756)

Immunogen

Peripheral membrane proteins extracted from Torpedo postsynaptic membranes.

Application

Anti-Dystrophin Antibody, clone 1808 detects level of Dystrophin & has been published & validated for use in WB, IH.
Western blot

Immunohistochemistry

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

By Western blot MAB1645 recognizes a single protein having a relative molecular weight of 300 kD. Reacts to mammalian skeletal muscle dystrophin. Shows no staining of mdx mouse muscle. Labels normal human muscle but not Duchenne muscle.

STAINING PATTERN:

On cryostat sections of normal mouse diaphragm MAB1645 gives strong immunofluorescence staining of the entire sarcolemma, with particularly strong staining of neuromuscular junctions.

SPECIES REACTIVITY:

Labels skeletal muscle from rat, chicken and Xenopus laevis. Labels cardiac muscle from rat and normal, but not mdx, mouse. Also labels smooth muscle from chicken gizzard.

Physical form

Format: Purified
Liquid in 0.02 M phosphate buffer (pH 7.6), 250 mM NaCl with 0.1% sodium azide.

Preparation Note

Maintain at -20ºC for up to 12 months in convenient aliquots. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

MAB1645:

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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