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MAB4148

Anti-MRP2 Antibody, clone M2 I-4

Name: Anti-MRP2 Antibody, clone M2 I-4
Brand: MM

culture supernatant, clone M2 I-4, Chemicon^®

Synonym(s):

cMOAT

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Clone:

M2 I-4, monoclonal

Species reactivity:

human

Application:

ICC, IHC, WB

Citations:

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Properties

biological source

mouse

Quality Segment

300

antibody form

culture supernatant

antibody product type

primary antibodies

clone

M2 I-4, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon^®

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable, western blot: suitable

isotype

IgG1

NCBI accession no.

NM_000392.2

UniProt accession no.

Q92887

shipped in

wet ice

Gene Information

human ... ABCC2(1244)

Description

Immunogen

Fusion protein of MRP2 containing aa 215-310 of the protein.

Application

This Anti-MRP2 Antibody, clone M2 I-4 is validated for use in WB, IC, IH for the detection of MRP2.

Western blotting: 1:20 - 1:50 with anti-mouse HRP

Immunocytochemistry: 1:20 - 1:50 on acetone fixed cytospin preparations

Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

This antibody reacts with an internal epitope of MRP2, a 190-200 kDa transmembrane protein previously known as the canalicular multi-organic anion transporter (cMOAT). MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. This antibody does not cross-react with the human MDR1, MRP1, MRP3 or MRP5 gene products.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

MAB4148:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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