Skip to Content
Merck

324413

Dynamin Inhibitor IV, Hydroxy-Dynasore

The Dynamin Inhibitor IV, Hydroxy-Dynasore controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Cell Signaling applications.

Synonym(s):

Dynamin Inhibitor IV, Hydroxy-Dynasore, 3-Hydroxynaphthalene-2-carboxylic acid-(2,4,5-trihydroxybenzylidene)-hydrazide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C18H14N2O5
Molecular Weight:
338.31
NACRES:
NA.77
UNSPSC Code:
12352200

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Dynamin Inhibitor IV, Hydroxy-Dynasore, The Dynamin Inhibitor IV, Hydroxy-Dynasore controls the biological activity of Dynamin. This small molecule/inhibitor is primarily used for Cell Signaling applications.

Quality Level

100

assay

≥97% (HPLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

yellow

solubility

DMSO: 100 mg/mL

shipped in

ambient

storage temp.

2-8°C

Related Categories

Disclaimer

Toxicity: Standard Handling (A)

Other Notes

Harper, C.B., et al. 2011. J. Biol. Chem.286, 35966.
Howes, M.T., et al. 2010. J. Cell Biol.190, 675.

Packaging

Packaged under inert gas

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

General description

A highly potent (IC50 = 0.38 and 2.6 µM for dynamin I and dynamin II, respectively), cell-permeable and in vivo bioavailable (30 mg/kg in mice, i.p.) hydroxylated analog of Dynamin Inhibitor I, Dynasore (Cat. No. 324410 ).

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Enikő Pergel et al.
International journal of molecular sciences, 22(19) (2021-10-14)
TMEM175 (transmembrane protein 175) coding sequence variants are associated with increased risk of Parkinson's disease. TMEM175 is the ubiquitous lysosomal K+ channel regulated by growth factor receptor signaling and direct interaction with protein kinase B (PKB/Akt). In the present study

Global Trade Item Number

SKUGTIN
324413-10MGCN04055977197198

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service