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Merck

MAB80121

Anti-Human Metapneumovirus Antibody, clone 36

clone 36, Chemicon®, from mouse

Synonym(s):

hMPV

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.42
eCl@ss:
32160702
Clone:
36, monoclonal
Species reactivity:
human
Application:
ELISA
flow cytometry
immunofluorescence
Technique(s):
ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
Citations:
5

Key Documents

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Product Name

Anti-Human Metapneumovirus Antibody, clone 36, clone 36, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

36, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable

isotype

IgG2a

shipped in

wet ice

Quality Level

300

Related Categories

Application

Detect Human Metapneumovirus using this Anti-Human Metapneumovirus Antibody, clone 36 validated for use in ELISA, FC & IF.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

Biochem/physiol Actions

Specific to the nuclear protein. Reactive with all sub-types; A1, A2, B1, B2.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Human metapneumovirus (hMPV) is a member of the pneumovirinae subfamily of paramyxoviruses, first described in 2001 from pediatric respiratory specimens in the Netherlands. It is an enveloped pleomorphic virus with a single negative-strand RNA genome. Two major serotypes, A and B, have been described. Several studies identified hMPV in specimens worldwide, and estimated that by age 5 years 70% of children have developed antibodies to hMPV.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Liquid in 0.02M PB with 0.25M NaCl, pH 7.6. Contains 0.1% sodium azide.

Preparation Note

Store at 2° to 8°C for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

MAB80121:

jan

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Fernando Villalón-Letelier et al.
mBio, 12(5), e0148421-e0148421 (2021-09-15)
Membrane-associated RING-CH8 (MARCH8) impairs the cell surface expression of envelope glycoproteins from different viruses, reducing their incorporation into virions. Using stable cell lines with inducible MARCH8 expression, we show that MARCH8 did not alter susceptibility to influenza A virus (IAV)
Kathleen M Nitschinsk et al.
Intervirology, 61(3), 149-154 (2018-08-27)
Human metapneumovirus (hMPV) is an important human respiratory pathogen and is implicated in an array of respiratory illnesses, ranging from asymptomatic infection to severe bronchiolitis. Currently, there is no reliable vaccine or specific antiviral therapy for hMPV infection and treatment
Leah Gillespie et al.
Journal of virology, 90(17), 7848-7863 (2016-06-24)
It is well established that glycosaminoglycans (GAGs) function as attachment factors for human metapneumovirus (HMPV), concentrating virions at the cell surface to promote interaction with other receptors for virus entry and infection. There is increasing evidence to suggest that multiple
Human metapneumovirus associated with respiratory tract infections in a 3-year study of nasal swabs from infants in Italy.
Maggi, Fabrizio, et al.
Journal of Clinical Microbiology, 41, 2987-2991 (2003)

Global Trade Item Number

SKUGTIN
MAB8012104053252723742

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