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Merck

252549

Formaldehyde solution

37 wt. % in H₂O, solution, ACS reagent grade,contains 10-15% methanol as stabilizer (to prevent polymerization)

Synonym(s):

Formalin

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About This Item

Linear Formula:
HCHO
CAS Number:
50-00-0
Molecular Weight:
30.03
NACRES:
NA.21
PubChem Substance ID:
24855218
UNSPSC Code:
12352114
MDL number:
MFCD00003274
Beilstein/REAXYS Number:
1209228
Form:
liquid

Key Documents

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Product Name

Formaldehyde solution, ACS reagent, 37 wt. % in H2O, contains 10-15% Methanol as stabilizer (to prevent polymerization)

InChI

1S/CH2O/c1-2/h1H2

SMILES string

[H]C([H])=O

InChI key

WSFSSNUMVMOOMR-UHFFFAOYSA-N

grade

ACS reagent

vapor density

1.03 (vs air)

vapor pressure

52 mmHg ( 37 °C), 52 mmHg ( 37 °C)

form

liquid

autoignition temp.

572 °F

contains

10-15% Methanol as stabilizer (to prevent polymerization)

concentration

36.5-38.0%, 37 wt. % in H2O

impurities

≤0.006 meq/g Titr. acid

ign. residue

≤0.005%

color

APHA: ≤10

refractive index

n20/D 1.3765

solubility

water: soluble

density

1.09 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤5 ppm, sulfate (SO42-): ≤0.002%

cation traces

Fe: ≤5 ppm, heavy metals: ≤5 ppm (by ICP-OES)

suitability

suitable for manufacturing use (Laboratory chemicals)

Quality Level

200

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General description

Formaldehyde (formalin) is produced by oxidation of methanol. It is made of 37% formaldehyde and impurities such as methanol, small amounts of formic acid, aldehydes and ketones. It is used as a denaturant in formaldehyde-agarose gel electrophoresis of RNA.

Application

Formaldehyde solution has been used as a fixing agent to fix cells during immunofluorescence imaging and for cross-linking cells during chromatin immunoprecipitation (ChIP) assay.
Formaldehyde solution has been used for cross-linking/fixing of cells in ChIP (chromatin immunoprecipitation) assay. It has been used for fixing of cells for imaging.

Physical form

This product is a solution of approximately 37% by weight of formaldehyde gas in water.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 1 - STOT SE 3

target_organs

Eyes,Central nervous system, Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

132.8 °F - closed cup

flash_point_c

56 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Specified Class I Designated Chemical Substances

prtr

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

252549-12X500ML:4548173252438 + 252549-BULK: + 252549-3L: + 252549-4X100ML: + 252549-500ML:4548173124933 + 252549-60KG: + 252549-100ML:4548173914152 + 252549-1L: + 252549-VAR: + 252549-4X2.5L: + 252549-500ML-CH: + 252549-6X1L: + 252549-4L:4548173124926 + 252549-138RN-150ML: + 252549-2.5L: + 252549-6X500ML:4548173124940 + 252549-EW: + 252549-25ML:4548173124919

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ6883
MKCW1343
MKCV9749
MKCX0729
MKCV9260

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