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Merck

434760

Benzamidine hydrochloride

99%

Synonym(s):

Amidinobenzene hydrochloride, Benzamidinium chloride

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About This Item

Linear Formula:
C6H5C(=NH)NH2 · HCl
CAS Number:
1670-14-0
Molecular Weight:
156.61
UNSPSC Code:
12352106
NACRES:
NA.77
PubChem Substance ID:
24867207
EC Number:
216-795-4
Beilstein/REAXYS Number:
3594959
MDL number:
MFCD00013025

Key Documents

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Product Name

Benzamidine hydrochloride, 99%

InChI key

LZCZIHQBSCVGRD-UHFFFAOYSA-N

InChI

1S/C7H8N2.ClH/c8-7(9)6-4-2-1-3-5-6;/h1-5H,(H3,8,9);1H

SMILES string

Cl.NC(=N)c1ccccc1

assay

99%

form

beads

mp

169-173 °C (lit.)

solubility

water: soluble

Quality Level

200

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Application

<ul>
<li><strong>Purification and characterization of a serine protease from organic dust and elucidation of its inductive effects on lung i</strong></li>
<li><strong>Preclinical testing of dabigatran in trypsin-dependent pancreatitis:</strong> This research uses Benzamidine hydrochloride to inhibit serine proteases in models of pancreatitis, highlighting its potential in preclinical studies to evaluate new therapeutic approaches for inflammatory and digestive disorders (Pesei et al., 2022).</li>
</ul>

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

434760-BULK: + 434760-VAR: + 434760-25G: + 434760-5G:

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Certificates of Analysis (COA)

Lot/Batch Number
MKCZ6258
0000488065
0000488065
WXBF6905V
0000358947

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Bradley S Heater et al.
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iScience, 23(6), 101158-101158 (2020-05-29)
The effectiveness of cancer radiotherapy is frequently hindered by the hypoxia of the tumor microenvironment. Direct delivery of oxygen to hypoxic tumor tissues is an attractive strategy to overcome this hypoxia-associated radioresistance. Herein, we report the generation of submicron-sized particles
Seweryn Mroczek et al.
Nature communications, 8(1), 619-619 (2017-09-22)
FAM46C is one of the most frequently mutated genes in multiple myeloma. Here, using a combination of in vitro and in vivo approaches, we demonstrate that FAM46C encodes an active non-canonical poly(A) polymerase which enhances mRNA stability and gene expression.
Marta M Nowacka-Chmielewska et al.
Pharmacological reports : PR, 69(3), 520-525 (2017-04-01)
Stress is a major predisposing factor in the development of psychiatric disorders and potential source of augmented inflammatory processes in the brain. Increasing body of evidence shows an important role of alterations in the olfactory bulbs (OBs) function in stress-related
Joris Van Lindt et al.
Communications biology, 4(1), 77-77 (2021-01-21)
Understanding the kinetics, thermodynamics, and molecular mechanisms of liquid-liquid phase separation (LLPS) is of paramount importance in cell biology, requiring reproducible methods for studying often severely aggregation-prone proteins. Frequently applied approaches for inducing LLPS, such as dilution of the protein
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