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Merck

534056

Xylenes

histological grade

Synonym(s):

Xylene mixture of isomers

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About This Item

Linear Formula:
C6H4(CH3)2
CAS Number:
1330-20-7
Molecular Weight:
106.17
NACRES:
NA.21
PubChem Substance ID:
329757880
UNSPSC Code:
12352002
MDL number:
MFCD00077264
Assay:
≥75.0% (xylenes isomers)
Bp:
137-140 °C (lit.)
Vapor pressure:
18 mmHg ( 37.7 °C)

Key Documents

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InChI

1S/3C8H10/c1-7-3-5-8(2)6-4-7;1-7-4-3-5-8(2)6-7;1-7-5-3-4-6-8(7)2/h3*3-6H,1-2H3

SMILES string

Cc1ccc(C)cc1.Cc2cccc(C)c2.Cc3ccccc3C

InChI key

MVZVDAGWAAZJPE-UHFFFAOYSA-N

vapor density

3.7 (vs air)

vapor pressure

18 mmHg ( 37.7 °C)

assay

≥75.0% (xylenes isomers)

Quality Level

100

expl. lim.

7 %

impurities

≤0.05% (water), ≤25% ethylbenzene

evapn. residue

<0.002%

refractive index

n20/D 1.497 (lit.)

bp

137-140 °C (lit.)

mp

-34 °C

density

0.86 g/mL at 25 °C (lit.)

application(s)

histology

storage temp.

room temp

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General description

Xylenes are an isomeric mixture of aromatic hydrocarbons namely, o-xylene, m-xylene, and p-xylene. It is used as a solvent in the pharmaceutical, printing, rubber, cleaning agent, paint thinner, varnish, synthetic fiber, and leather industries.

Application

Xylenes (histological grade) can be used as a clearing agent in routine histology and cytology applications to remove paraffin from tissue section slides before staining.
It can be used in:      
  • Cresyl violet staining.     
  • Fluoro-Jade B staining process.      
  • Giemsa cell staining protocols.

Packaging

20 L in steel drum


500 mL in glass bottle


534056-4L , 4×4 L in glass bottle

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Asp. Tox. 1 - Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT RE 2 - STOT RE 2 Inhalation - STOT SE 3

target_organs

Central nervous system,Liver,Kidney, hearing organs, Respiratory system

Storage Class

3 - Flammable liquids

flash_point_f

77.0 °F - closed cup

flash_point_c

25 °C - closed cup

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Deleterious substance

pdsc

Class I Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 2 petroleums + Hazardous rank III + Water insoluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

534056-20L:4548173167169 + 534056-BULK: + 534056-4X4L: + 534056-1L:4548173269962 + 534056-18L-CS: + 534056-4L:4548173167176 + 534056-VAR: + 534056-500ML:4548173167183

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Certificates of Analysis (COA)

Lot/Batch Number
SHBT5947
SHBT6541
SDBB7538
SHBT6540
BCCP1856

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Assessment of paraffin removal from prostate FFPE sections using transmission mode FTIR-FPA imaging.
Hughes C, et al.
Analytical Methods : Advancing Methods and Applications, 6(4), 1028-1035 (2014)
Fluoro-Jade B Staining for Neuronal Cell Death.
Laflamme N, et al.
Bio-protocol, 6(1) (2016)
Electron ionization of o-xylene, m-xylene and p-xylene.
Jiao CQ and Adams SF.
Chemical Physics Letters, 573, 24-28 (2013)
Experimental and modeling study of the oxidation of xylenes.
Battin-Leclerc F, et al.
International Journal of Chemical Kinetics, 38(4), 284-302 (2006)
A survey of household products for volatile organic compounds.
Sack TM, et al.
Atmos. Environ., Part A, 26(6), 1063-1070 (1992)
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