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Merck

F7503

Formamide

ReagentPlus®, ≥99.0% (GC)

Synonym(s):

Amide C1, Formic amide

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About This Item

Linear Formula:
HCONH2
CAS Number:
Molecular Weight:
45.04
UNSPSC Code:
12352111
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-842-0
Beilstein/REAXYS Number:
505995
MDL number:
Assay:
≥99.0% (GC)
Technique(s):
hybridization: suitable
Bp:
210 °C (lit.)
Vapor pressure:
0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)
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vapor density

1.55 (vs air)

Quality Level

vapor pressure

0.08 mmHg ( 20 °C), 30 mmHg ( 129 °C)

product line

ReagentPlus®

assay

≥99.0% (GC)

form

liquid

autoignition temp.

932 °F

expl. lim.

2.7-19 %

technique(s)

hybridization: suitable

refractive index

n20/D 1.447 (lit.)

pH

4-10 (20 °C, 200 g/L)

bp

210 °C (lit.)

mp

2-3 °C (lit.)

density

1.134 g/mL at 25 °C (lit.)

SMILES string

NC=O

InChI

1S/CH3NO/c2-1-3/h1H,(H2,2,3)

InChI key

ZHNUHDYFZUAESO-UHFFFAOYSA-N

General description

Formamide is a polar solvent mainly used for resins and plasticizers. It can be prepared by direct synthesis from carbon monoxide and ammonia.

Application

Formamide can be used as a solvent:
  • To synthesize tetrakis(trialkylsilyl) diphosphate by reacting disodium dihydrogen diphosphate with trialkyl chlorosilane.
  • In Cu/C catalyzed cycloaddition between azides and terminal alkynes to synthesize triazoles.
Formamide destabilizes nucleic acid duplexes and may be used, typically, at a concentration of 50%, in hybridization protocols requiring lower hybridization temperatures.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 2 - Repr. 1B - STOT RE 2 Oral

target_organs

Blood

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 1

flash_point_f

305.6 °F

flash_point_c

152 °C


Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Class II Designated Chemical Substances

prtr

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

F7503-1L:4.548173196855E12 + F7503-500ML:4.548173196886E12 + F7503-100ML:4.548173196848E12 + F7503-5ML:4.548173196893E12 + F7503-250ML:4.548173196879E12 + F7503-4L:4.548173925332E12 + F7503-2.5L:4.548173196862E12

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Related Content

Product Information Sheet


The crystal structure of formamide.
Ladell J and Post B.
Acta Crystallographica, 7(8-9), 559-564 (1954)
The formamide method for the extraction of polysaccharides from haemolytic streptococci.
Fuller AT.
British Journal of Experimental Pathology, 19(2), 130-130 (1938)
Microwave spectrum, structure, dipole moment, and quadrupole coupling constants of formamide.
Kurland RJ and Wilson Jr EB.
J. Chem. Phys. , 27(2), 585-590 (1957)