Skip to Content
Merck

Key Documents

View All Documentation

14366C

EX-CELL® Advanced CHO Fed-batch Medium

liquid

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

NACRES:
NA.75
UNSPSC Code:
41161501
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

sterility

sterile-filtered

Quality Level

500

product line

EX-CELL®

form

liquid

feature

subscription eligible

technique(s)

cell culture | mammalian: suitable (suspension)

components

L-glutamine: no

shipped in

ambient

storage temp.

2-8°C

General description

EX-CELL® AdvancedCHO Fed-batch Medium is chemically-defined and contains no animal derived components. This newest platform from SAFC has been specifically developed to support growth and productivity across a diverse set of Chinese Hamster Ovary (CHO) cells in fed-batch cultures while still allowing for flexibility in the adjustment of protein quality attributes. This contemporary fed-batch platform was developed using a strategy of Multivariate Analysis to establish correlations in which the formulation components influence critical process and product attributes such as titer, fold expansion, receptor expression, and glycosylation. This platform contains no hypoxanthine and thymidine, L-glutamine, phenol red or 2-mercaptoethanol (2-ME). This medium is intended to be a part of a fed-batch platform, and used with EX-CELL® Advanced CHO Feed 1 (24367C - with glucose or 24368C - without glucose).

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Donot freeze. Protect from light. Several components of the medium arelight labile and should not be exposed to light for lengthy periods of time.

Still not finding the right product?

Explore all of our products under EX-CELL® Advanced CHO Fed-batch Medium

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

14366C-20B: + 14366C-BULK: + 14366C-PROC: + 14366C-100BD: + 14366C-10B: + 14366C-1000ML: + 14366C-5B: + 14366C-1BAF: + 14366C-100BDAF: + 14366C-VAR: + 14366PROC: + 14366C-200BD: + 14366C-10X1B: + 14366C-2X5B: + 14366CPROC: + 14366C-50B: + 14366C-200BFS: + 14366C-1B: + 14366C-200BDAF: + 14366C-500BFS: + 14366C-10BAF: + 14366C-100BFS: + 14366C-PH:

jan

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000497763
0000497767
0000497767
0000497763
0000415524

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Low-Impurity Iron Sources: Case Studies in EX-CELL® Advanced Medium

Discover how low-impurity iron sources improve reliability and performance in recombinant protein production with EX-CELL® Advanced medium.

Upstream Bioprocessing Feed Strategies and Scalability: A Case Study with Cellvento® ModiFeed Prime COMP

This case study walks through optimizing feed and media for upstream bioprocessing and how it translates to large-scale bioreactors.

CHO Media and Feeds for Optimized Production of Therapeutic Proteins

Cellvento® and EX-CELL® CHO cell culture media and feeds, optimized for monoclonal antibody & recombinant protein production in fed-batch & perfusion

View All Articles

Related Content

Cell Culture Media Development for mAbs

Learn more about cell culture media development for mAB development and manufacturing, and the products you need for this step.

Glycosylation Modulation in Fed-batch Production of Therapeutic Proteins

Enhance mAb and recombinant protein performance, efficacy, and stability with precise glycosylation modulation using the Cellvento® ModiFeed platform.

Weiyi Liu et al.
Biotechnology progress, 37(1), e3061-e3061 (2020-08-05)
Antibody-dependent cellular cytotoxicity (ADCC) is the primary mechanism of actions for several marketed therapeutic antibodies (mAbs) and for many more in clinical trials. The ADCC efficacy is highly dependent on the ability of therapeutic mAbs to recruit effector cells such