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A0788

3-Aminobenzamide

Name: 3-Aminobenzamide
Brand: SIGMA

≥99% (TLC), PARP inhibitor, powder

Synonym(s):

3-AB, 3-ABA

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About This Item

Linear Formula:

H₂NC₆H₄CONH₂

CAS Number:

3544-24-9

Molecular Weight:

136.15

NACRES:

NA.77

PubChem Substance ID:

24278206

UNSPSC Code:

12352200

EC Number:

222-586-9

MDL number:

MFCD00007989

Assay:

≥99% (TLC)

Form:

powder

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Properties

Product Name

3-Aminobenzamide, ≥99% (TLC)

Quality Segment

200

assay

≥99% (TLC)

form

powder

color

white to off-white

mp

115-116 °C (lit.)

solubility

ethanol: 50 mg/mL, clear, light yellow, DMSO: soluble, H₂O: soluble (may require gentle heating)

storage temp.

room temp

SMILES string

NC(=O)c1cccc(N)c1

InChI

1S/C7H8N2O/c8-6-3-1-2-5(4-6)7(9)10/h1-4H,8H2,(H2,9,10)

InChI key

GSCPDZHWVNUUFI-UHFFFAOYSA-N

Gene Information

mouse ... Parp1(11545)

Description

Application

3-Aminobenzamide has been used as a poly-(ADP-ribose) polymerase (PARP) inhibitor in various experimental studies.

Biochem/physiol Actions

3-Aminobenzamide enhances cell death, unscheduled DNA synthesis and repair replication by interrupting the rejoining of DNA strand breaks induced by both ionizing radiations and several alkylating agents. It has an ability to inhibit the activity of nuclear enzyme poly (ADP-ribose) synthetase (PARS). 3-Aminobenzamide exhibits protective action against myocardial reperfusion injury and local inflammation.

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Storage Class

11 - Combustible Solids

WGK

WGK 3

PPE (personal protective equipment)

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

A0788-250MG: + A0788-5G: + A0788-100MG: + A0788-VAR: + A0788-1G: + A0788-BULK:

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