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Merck

D4540

Dimethyl sulfoxide

≥99.5% (GC), suitable for plant cell culture

Synonym(s):

DMSO

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About This Item

Linear Formula:
(CH3)2SO
CAS Number:
67-68-5
Molecular Weight:
78.13
UNSPSC Code:
12191502
NACRES:
NA.71
PubChem Substance ID:
24893881
EC Number:
200-664-3
Beilstein/REAXYS Number:
506008
MDL number:
MFCD00002089
Assay:
≥99.5% (GC)
Technique(s):
cell culture | plant: suitable, cryopreservation: suitable
Bp:
189 °C (lit.)
Vapor pressure:
0.42 mmHg ( 20 °C)

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Quality Level

200

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

SMILES string

CS(C)=O

vapor density

2.7 (vs air)

vapor pressure

0.42 mmHg ( 20 °C)

assay

≥99.5% (GC)

form

liquid

autoignition temp.

573 °F

expl. lim.

42 %, 63 °F

technique(s)

cell culture | plant: suitable, cryopreservation: suitable

impurities

<0.1% water (Karl Fischer)

color

colorless

refractive index

n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

solubility

H2O: miscible (completely)

density

1.10 g/mL (lit.)

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Application

Dimethyl sulfoxide has been used:
  • in the preparation of bisphenol A (BPA)
  • in cell proliferation assay (MTT assay)
  • in chemosensitivity assay
  • as the vehicle control in all experiments like apoptosis assay
  • in ethoxyresorufin-O-deethylation (EROD) assay

Biochem/physiol Actions

DMSO (dimethyl sulfoxide), an organic solvent possesses several pharmaceutical activities such as analgesic, diuretic, bacteriostatic, membrane-penetrant, anti-inflammatory, vasodilatory and cholinesterase inhibitory effects. It is a by-product of the lumber industry and used as an industrial solvent. DMSO also serves as a therapeutic agent to treat interstitial cystitis and arthritis.

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

Disclaimer

Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

188.6 °F - closed cup

flash_point_c

87 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Group 4: Flammable liquids + Type 3 petroleums + Hazardous rank III + Water soluble liquid

fsl

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

D4540-500ML: + D4540-100ML: + D4540-1L: + D4540-VAR: + D4540-BULK:

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN6901
SHBT3256
PCCS8446
SHBT1983
SHBT1986

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