General description
Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details. Primary Human Hepatocytes are cells directly harvested from whole human livers and are used by researchers in vitro to model the physiology and function of Hepatocytes. As one of the major cell types of the liver, Hepatocytes function in protein, carbohydrate, and lipid metabolism and help to maintain liver homeostasis.
Application
Cryopreserved primary human plateable hepatocytes offer a versatile in vitro culture system, providing essential resources for investigating enzyme induction, toxicity, drug screening, transporter efflux activity, potential drug-drug interactions, and disease modeling.
Features and Benefits
Our plateable Hepatocytes collection consists of a homogeneous cell population, with each donor providing documented consent for research use of non-transplantable organs or tissues. These cells undergo extensive characterization, including mRNA induction data, enzyme profiling data, and morphological assessments, with a guaranteed post-thaw viability of ≥70%. In addition, all cells have been tested for the absence of HIV, HBV, HCV, Syphillis and microbial contaminants (fungi, bacteria, and mycoplasma).
Disclaimer
Each donor is tested and found non-reactive to viral DNA from HIV-1, HIV-2, HTLV I, HTLV II, hepatitis B and hepatitis C. However, no known test can offer complete assurance that the viruses that cause HIV-1, HIV-2, HTLV I, HTLV II, hepatitis B and hepatitis C are not present. Proper precautions and biological containment should be taken when handling cells of human origin, due to their potential biohazardous nature. All human based products should be handled at a BSL-2 (Biosafety Level 2) or higher.
This product is regulated in France when intended for scientific purposes, including import, export, and conservation activities (Articles L.1211-1, paragraph 2, and L.1243-4 of the French Public Health Code). The purchaser (i.e. end user) is required to obtain an import authorization from the France Ministry responsible for Research (as referenced in Article L.1245-5-1 II of the French Public Health Code) or a conservation authorization from the same ministry (as referenced in Article L.1243-4 of the French Public Health Code). By placing an order for this product, you confirm that you have obtained the appropriate import or conservation authorization for the product. For more information regarding the use of human biological samples for research purposes in France, please contact the relevant French authorities.