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Merck

L7026

Lithium chloride solution

8 M, Molecular Biology, ≥99%

Synonym(s):

LiCl

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About This Item

Linear Formula:
LiCl
CAS Number:
7447-41-8
Molecular Weight:
42.39
NACRES:
NA.31
PubChem Substance ID:
24896448
UNSPSC Code:
12352302
MDL number:
MFCD00011078
Assay:
≥99%
Grade:
Molecular Biology

Key Documents

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Product Name

Lithium chloride solution, 8 M, Molecular Biology, ≥99%

InChI

1S/ClH.Li/h1H;/q;+1/p-1

SMILES string

[Li+].[Cl-]

InChI key

KWGKDLIKAYFUFQ-UHFFFAOYSA-M

grade

Molecular Biology

assay

≥99%

concentration

8 M

anion traces

sulfate (SO42-): ≤0.01%

cation traces

Ba: ≤0.003%
Fe: ≤0.001%
K: ≤0.01%
Na: ≤0.20%
heavy metals (as Pb): ≤0.002%

foreign activity

DNase, RNase, protease, none detected

Quality Level

200

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Application

Lithium chloride solution has been used:
  • to obtain LiClPAM3 DCs form of dendritic cell
  • in LiCl buffer preparation for immunoprecipitation
  • in the preparation of wash buffer
  • in the preparation of radioimmunoprecipitation assay (RIPA) wash buffer

May be used to selectively precipitate RNA.

Biochem/physiol Actions

Lithium chloride has the ability to block glycogen synthase kinase (GSK). It may also possess anti-inflammatory effects at low and non-toxic concentrations.

Preparation Note

Prepared with 18 megaohm water
0.2 μm filtered

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

Substances Subject to be Indicated Names

ishl_indicated

Substances Subject to be Notified Names

ishl_notified

L7026-EW: + L7026-100ML-PW: + L7026-500ML:4548173201689 + L7026PROC: + L7026-BULK: + L7026-100ML:4548173201665 + L7026-1L:4548173201672 + L7026-VAR: + L7026-PH: + L7026-500ML-PW: + L7026-1L-PW:

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Certificates of Analysis (COA)

Lot/Batch Number
0000507922
0000507922
0000499627
0000499627
0000478383

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Micro-chromatin Immunoprecipation (muChIP) Protocol for Real-time PCR Analysis of a Limited Amount of Cells
Gillotin S and Guillemot F
Bio-protocol, 6(12), e0159986-e0159986 (2016)
RNA Chromatin Immunoprecipitation (RNA-ChIP) in Caenorhabditis elegans
Cecere G and Grishok A
Nature Structural and Molecular Biology (2014)
Allostimulatory Effects of Dendritic Cells with Characteristic Features of a Regulatory Phenotype
Kouwenberg M, et al.
PLoS ONE, 11(8), e0159986-e0159986 (2016)
mTOR and neuroinflammation
Molecules to Medicine with mTOR, 317-329 (2016)
Tong Ihn Lee et al.
Nature protocols, 1(2), 729-748 (2007-04-05)
Genome-wide location analysis, also known as ChIP-Chip, combines chromatin immunoprecipitation and DNA microarray analysis to identify protein-DNA interactions that occur in living cells. Protein-DNA interactions are captured in vivo by chemical crosslinking. Cell lysis, DNA fragmentation and immunoaffinity purification of
View All Related Papers

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