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I2401

Indazole

Name: Indazole
Brand: ALDRICH

98%

Synonym(s):

1,2-Benzodiazole, 1,2-Benzopyrazole

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About This Item

Empirical Formula (Hill Notation):

C₇H₆N₂

CAS Number:

271-44-3

Molecular Weight:

118.14

UNSPSC Code:

12352100

NACRES:

NA.22

PubChem Substance ID:

24895976

EC Number:

205-978-4

Beilstein/REAXYS Number:

109676

MDL number:

MFCD00005691

Assay:

98%

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Properties

Quality Level

100

assay

98%

bp

270 °C/743 mmHg (lit.)

mp

145-148 °C (lit.)

SMILES string

c1ccc2[nH]ncc2c1

InChI

1S/C7H6N2/c1-2-4-7-6(3-1)5-8-9-7/h1-5H,(H,8,9)

InChI key

BAXOFTOLAUCFNW-UHFFFAOYSA-N

Description

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Striking difference in antiproliferative activity of ruthenium- and osmium-nitrosyl complexes with azole heterocycles.

Gabriel E Büchel et al.

Inorganic chemistry, 52(11), 6273-6285 (2013-05-11)

Ruthenium nitrosyl complexes of the general formulas (cation)(+)[cis-RuCl4(NO)(Hazole)](-), where (cation)(+) = (H2ind)(+), Hazole = 1H-indazole (Hind) (1c), (cation)(+) = (H2pz)(+), Hazole = 1H-pyrazole (Hpz) (2c), (cation)(+) = (H2bzim)(+), Hazole = 1H-benzimidazole (Hbzim) (3c), (cation)(+) = (H2im)(+), Hazole = 1H-imidazole (Him)

Effects of TLR agonists on the hypoxia-regulated transcription factor HIF-1alpha and dendritic cell maturation under normoxic conditions.

Rolf Spirig et al.

PloS one, 5(6), e0010983-e0010983 (2010-06-12)

Dendritic cells (DC) are professional antigen presenting cells that represent an important link between innate and adaptive immunity. Danger signals such as toll-like receptor (TLR) agonists induce maturation of DC leading to a T-cell mediated adaptive immune response. In this

Modulation of ruthenium anticancer drugs analogs with tolfenamic acid: Reactivity, biological interactions and growth inhibition of yeast cell.

Priyaranjan Kumar et al.

Journal of inorganic biochemistry, 199, 110769-110769 (2019-07-22)

We synthesized two ruthenium(II) complexes: trans,trans-[Ru(im)2(tfa)2] (1) and trans,trans‑[Ru(in)2(tfa)2] (2) where im = 1H‑imidazole, in = 1H‑indazole and tfa = tolfenamic acid, a potential nonsteroidal anti-inflammatory drug (NSAID). The NSAID was opted as bioactive ligand to understand its synergistic therapeutic effect in structurally analogous Ru(II)-compounds with

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