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Merck

C0250

Sodium cacodylate trihydrate

≥98%

Synonym(s):

Cacodylic acid sodium salt trihydrate, Dimethylarsinic acid sodium salt, Dimethylarsonic acid sodium salt

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About This Item

Linear Formula:
(CH3)2AsO2Na · 3H2O
CAS Number:
6131-99-3
Molecular Weight:
214.03
UNSPSC Code:
12161700
NACRES:
NA.21
PubChem Substance ID:
24892242
EC Number:
204-708-2
Beilstein/REAXYS Number:
3702348
MDL number:
MFCD00149079

Product Name

Sodium cacodylate trihydrate, ≥98%

SMILES string

[Na+].[H]O[H].[H]O[H].[H]O[H].C[As](C)([O-])=O

InChI key

RLGWPHBPRCROJO-UHFFFAOYSA-M

InChI

1S/C2H7AsO2.Na.3H2O/c1-3(2,4)5;;;;/h1-2H3,(H,4,5);;3*1H2/q;+1;;;/p-1

assay

≥98%

form

powder

pH

5.1-7.4

pKa (25 °C)

6.27

solubility

water: 100 mg/mL, clear, colorless

application(s)

ADME/TOX

storage temp.

room temp

Quality Level

200

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Application

Sodium cacodylate trihydrate has been used in the stabilization of the fixatives for electron microscopy. It has also been used to collect vibratome sections to perform nucleoside-diphosphatase technique.

General description

Sodium cacodylate is an organic arsenic compound that is metabolized to produce inorganic, trivalent arsenic in vivo. Sodium cacodylate has been used as a source of arsenic in toxicological research. It is used as a buffer with an effective pH buffering range of 5.1-7.4. In microscopy studies, the buffering capacity of cacodylate prevents excess acidity that may result from tissue fixation.

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Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B

Storage Class

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN0647
BCCL8961
BCCK3780
BCCH7696
BCCG7114

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Cytotoxic effect of three arsenic compounds in HeLa human tumor and bacterial cells
Abdullaev F, et al.
Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 493(1), 31-38 (2001)
Imaging myelinated nerve fibres by confocal fluorescence microscopy: individual fibres in whole nerve trunks traced through multiple consecutive internodes
Reynolds RJ, et al.
Journal of Neurocytology, 23(9), 555-564 (1994)
A pre-embedding technique for immunocytochemical visualization of cathepsin D in cultured cells subjected to oxidative stress
Roberg K and Ollinger K
The Journal of Histochemistry and Cytochemistry, 46(3), 411-418 (1998)
Subcellular adaptation of the human diaphragm in chronic obstructive pulmonary disease
Orozco LM, et al.
The European Respiratory Journal, 13(2), 371-378 (1999)
Giorgia Montalbano et al.
Nanomaterials (Basel, Switzerland), 10(9) (2020-09-02)
Bone-tissue regeneration induced by biomimetic bioactive materials is the most promising approach alternative to the clinical ones used to treat bone loss caused by trauma or diseases such as osteoporosis. The goal is to design nanostructured bioactive constructs able to
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