146358
1-Ethyl-2-pyrrolidone
98%
Synonym(s):
NEP
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About This Item
Empirical Formula (Hill Notation):
C6H11NO
CAS Number:
Molecular Weight:
113.16
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
220-250-6
Beilstein/REAXYS Number:
107971
MDL number:
Assay:
98%
Form:
liquid
Quality Level
assay
98%
form
liquid
refractive index
n20/D 1.465 (lit.)
bp
97 °C/20 mmHg (lit.)
density
0.992 g/mL at 25 °C (lit.)
SMILES string
CCN1CCCC1=O
InChI
1S/C6H11NO/c1-2-7-5-3-4-6(7)8/h2-5H2,1H3
InChI key
ZFPGARUNNKGOBB-UHFFFAOYSA-N
General description
1-Ethyl-2-pyrrolidone is a transdermal absorption-enhancing compound and mechanism of its effect on multilammellar liposome of stratum corneum lipid has been studied.
Application
1-Ethyl-2-pyrrolidone was used to modify coir fiber (from Cocos nucifera) by photocuring.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Repr. 1B
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
flash_point_f
195.8 °F - Pensky-Martens closed cup
flash_point_c
91 °C - Pensky-Martens closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
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Xiaolei Zhu et al.
Aging cell, 16(5), 1073-1082 (2017-08-05)
The accumulation and deposition of beta-amyloid (Aβ) is a key neuropathological hallmark of Alzheimer's disease (AD). Histone deacetylases (HDACs) are promising therapeutic targets for the treatment of AD, while the specific HDAC isoforms associated with cognitive improvement are poorly understood.
Effect of Pretreatment with Ultraviolet Radiation on the Physicomechanical Properties of Photocured Coir (Cocos nucifera) Fiber with 1-Ethyl-2-Pyrrolidone (1-E-2-P) Monomer.
Khan MA, et al.
Polymer-Plastics Technology and Engineering, 45(4), 487-494 (2006)
Takeshi Katsuda et al.
Scientific reports, 3, 1197-1197 (2013-02-05)
Alzheimer's disease (AD) is characterized by the accumulation of β-amyloid peptide (Aβ) in the brain because of an imbalance between Aβ production and clearance. Neprilysin (NEP) is the most important Aβ-degrading enzyme in the brain. Thus, researchers have explored virus-mediated