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Merck

18588

Cefixime trihydrate

suitable for microbiology, ≥98.0% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C16H15N5O7S2 · 3H2O
CAS Number:
Molecular Weight:
507.50
NACRES:
NB.61
PubChem Substance ID:
UNSPSC Code:
26111700
MDL number:
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Product Name

Cefixime trihydrate, suitable for microbiology, ≥98.0% (HPLC)

InChI

1S/C16H15N5O7S2.3H2O/c1-2-6-4-29-14-10(13(25)21(14)11(6)15(26)27)19-12(24)9(20-28-3-8(22)23)7-5-30-16(17)18-7;;;/h2,5,10,14H,1,3-4H2,(H2,17,18)(H,19,24)(H,22,23)(H,26,27);3*1H2/b20-9-;;;/t10-,14-;;;/m1.../s1

SMILES string

O.O.O.Nc1nc(cs1)C(=N\OCC(O)=O)\C(=O)N[C@H]2[C@H]3SCC(C=C)=C(N3C2=O)C(O)=O

InChI key

IPYWNMVPZOAFOQ-NABDTECSSA-N

description

for ion-selective electrodes

assay

≥98.0% (HPLC)

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

application(s)

microbiology

mode of action

cell wall synthesis | interferes

Quality Level

Other Notes

Determination of ytterbium in mineral probes (e.g. Zeolith-catalysts, Xenotime,...)

General description

Chemical structure: ß-lactam
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Analysis Note

Soluble in methanol and propylene glycol; slightly soluble in alcohol in acetone and in glycerin; very slightly soluble in 70% sorbitol and in octanol; practically insoluble in ether, in ethyl acetate, in hexane and in water

Application


  • Physicochemical parameters and modes of interaction associated with the micelle formation of a mixture of tetradecyltrimethylammonium bromide and cefixime trihydrate: effects of hydrotropes and temperature.: This research delves into the physicochemical behaviors of cefixime trihydrate when mixed with tetradecyltrimethylammonium bromide, focusing on micelle formation and the influence of various hydrotropes and temperature changes on their interaction (Hossain M et al., 2023).

  • Development, validation and greenness assessment of a new electro-driven separation method for simultaneous analysis of cefixime trihydrate and linezolid in their fixed dose combination.: This study introduces and validates a novel eco-friendly electro-driven method for analyzing cefixime trihydrate in combination with linezolid, emphasizing its application in fixed-dose pharmaceutical formulations (Habeeb MR et al., 2023).

  • Bioremediation of multifarious pollutants using laccase immobilized on magnetized and carbonyldiimidazole-functionalized cellulose nanofibers.: Investigates the efficacy of laccase enzymes, immobilized on specialized cellulose nanofibers, in the bioremediation of pollutants, a process applicable to the environmental management of pharmaceutical agents including cefixime trihydrate (Sharma K et al., 2023).

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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G M Baranzoni et al.
Journal of applied microbiology, 122(3), 809-816 (2016-12-18)
To evaluate the performance of the IQ-Check kits and the USDA Microbiology Laboratory Guidebook (MLG) methods for detection of the top seven Shiga toxin-producing Escherichia coli (STEC) (O157:H7, O26, O45, O103, O111, O121 and O145) in ground beef and both
Sanga Kang et al.
Journal of food protection, 83(10), 1812-1821 (2020-06-06)
There is increasing evidence that diversity changes in bacterial communities of beef cattle correlate to the presence of Shiga toxin-producing Escherichia coli (STEC). However, studies that found an association between STEC and bacterial diversity have been focused on preslaughter stages
T Fujisawa et al.
Applied and environmental microbiology, 66(7), 3117-3118 (2000-07-06)
A modified version of sorbitol MacConkey medium containing cefixime and tellurite (CT-SMAC medium) was produced by adding salicin and 4-methylumbelliferyl-beta-D-galactopyranoside to CT-SMAC medium; this medium was designated CT-SSMAC medium and was used to isolate Escherichia coli O157:H7 from radish sprouts.
D Rapp et al.
Microbial ecology, 81(1), 67-77 (2020-06-21)
Shiga toxin-producing Escherichia coli (STEC) are foodborne bacterial pathogens, with cattle a significant reservoir for human infection. This study evaluated environmental reservoirs, intermediate hosts and key pathways that could drive the presence of Top 7 STEC (O157:H7, O26, O45, O103
Luca Rotundo et al.
International journal of food microbiology, 291, 59-64 (2018-11-20)
In this study real-time PCR assays were evaluated for the detection of enteroaggregative hemorrhagic Escherichia coli (EAHEC) O104:H4 in artificially contaminated mung bean and/alfalfa sprouts inoculated with 1, 10, and 100 CFU of EAHEC O104:H4 per 25 g sample (20, 10, and

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